Sennacherib (Neo-Assyrian Akkadian: 𒀭𒌍𒉽𒈨𒌍𒋢, romanized: Sîn-aḥḥī-erība or Sîn-aḥḥē-erība, meaning "Sîn has replaced the brothers") was the king of the Neo-Assyrian Empire from 705 BC until his assassination in 681 BC. The second king of the Sargonid dynasty, Sennacherib is one of the most famous Assyrian kings for the role he plays in the Hebrew Bible, which describes his campaign in the Levant. Other events of his reign include his destruction of the city of Babylon in 689 BC and his renovation and expansion of the last great Assyrian capital, Nineveh.
Although Sennacherib was one of the most powerful and wide-ranging Assyrian kings, he faced considerable difficulty in controlling Babylonia, which formed the southern portion of his empire. Many of Sennacherib's Babylonian troubles stemmed from the Chaldean tribal chief Marduk-apla-iddina II, who had been Babylon's king until Sennacherib's father defeated him. Shortly after Sennacherib inherited the throne in 705 BC, Marduk-apla-iddina retook Babylon and allied with the Elamites. Though Sennacherib reclaimed the south in 700 BC, Marduk-apla-iddina continued to trouble him, probably instigating Assyrian vassals in the Levant to rebel, leading to the Levantine War of 701 BC, and himself warring against Bel-ibni, Sennacherib's vassal king in Babylonia.