The Museum of Science and Industry (MSI; formally Kenneth C. Griffin Museum of Science and Industry since 2024) is a private, non-profit science museum located in Jackson Park, the Hyde Park neighborhood, Chicago, Illinois. It is adjacent to Lake Michigan and the University of Chicago campus.
The museum is housed in the Palace of Fine Arts from the 1893 World's Columbian Exposition. Initially endowed by Sears, Roebuck and Company president and philanthropist Julius Rosenwald and supported by the Commercial Club of Chicago, it opened in 1933 during the Century of Progress Exposition. It was renamed for benefactor and financier Kenneth C. Griffin on May 19, 2024.