The Museum of Santa Cruz (Spanish: Museo de Santa Cruz) is an art, archaeology and ethnographic museum located in the historic centre of the city of Toledo, Spain. It exhibits collections pertaining to the province of Toledo, including works painted by El Greco in the city of Toledo.
The museum is housed in an architecturally significant 16th-century building, the Hospital de Santa Cruz, which has been protected by a heritage designation, currently Bien de Interés Cultural, since 1902.
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