Multicellular organisms in the context of "Unicellular organisms"

In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type.

In mammals, roughly 50 to 150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. In vivo, they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However, when they are isolated and cultured in vitro, they can be kept in the stem-cell stage and are known as embryonic stem cells (ESCs).

Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix (ECM), a gel-like structure containing molecules released by cells into spaces between them. Cell adhesion occurs from the interactions between cell adhesion molecules (CAMs), transmembrane proteins located in the cell membrane. Cell adhesion links cells in different ways and can be involved in signal transduction for cells to detect and respond to changes in the surroundings. Other cellular processes regulated by cell adhesion include cell migration and tissue development in multicellular organisms. Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthritis. Cell adhesion is also essential for infectious organisms, such as bacteria or viruses, to cause disease.

Flesh is any aggregation of soft tissues of an organism. Various multicellular organisms have soft tissues that may be called "flesh". In mammals, including humans, flesh encompasses muscles, fats and other loose connective tissues, but sometimes excludes non-muscular organs (liver, lung, spleen, kidney) and typically discarded parts (hard tendon, brain tissue, intestines, etc.). More generally, it may be considered the portions of the body that are soft and delicate. In a culinary context, consumable animal flesh is called meat, while processed visceral tissues are known as offal.

In particular animal groups such as vertebrates, molluscs and arthropods, the flesh is distinguished from tougher body structures such as bone, shell and scute, respectively. In plants, the "flesh" is the juicy, edible structures such as the mesocarp of fruits and melons as well as soft tubers, rhizomes and taproots, as opposed to tougher structures like nuts and stems. In fungi, flesh refers to trama, the soft, inner portion of a mushroom, or fruit body.