Merck Group in the context of KGaA

Darmstadt (/ˈdɑːrmstæt/ DARM-stat, UK also /-ʃtæt/ -⁠shtat, US also /-stɑːt, -ʃtɑːt/ -⁠s(h)taht, German: [ˈdaʁmʃtat] ) is a city in the state of Hesse in Germany, located in the southern part of the Rhine-Main-Area (Frankfurt Metropolitan Region). Darmstadt has around 160,000 inhabitants, making it the fourth largest city in the state of Hesse after Frankfurt am Main, Wiesbaden, and Kassel.

Darmstadt holds the official title "City of Science" (German: Wissenschaftsstadt) as it is a major centre of scientific institutions, universities, and high-technology companies. The European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT) and the European Space Agency's European Space Operations Centre (ESA ESOC) are located in Darmstadt, as well as GSI Centre for Heavy Ion Research, where several chemical elements such as darmstadtium, roentgenium, and copernicium were discovered. The existence of several elements was also confirmed at the GSI Centre. The Facility for Antiproton and Ion Research (FAIR) is an international accelerator facility under construction. Darmstadt is also the seat of the world's oldest pharmaceutical company, Merck, which is the city's largest employer.

3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (tablet form), and molly (crystal form), is an entactogen with stimulant and minor psychedelic properties.

MDMA was first synthesized in 1912 by Merck chemist Anton Köllisch. It was used to enhance psychotherapy beginning in the 1970s and became popular as a street drug in the 1980s. MDMA is commonly associated with dance parties, raves, and electronic dance music. Tablets sold as ecstasy may be mixed with other substances such as ephedrine, amphetamine, and methamphetamine. In 2016, about 21 million people between the ages of 15 and 64 used ecstasy (0.3% of the world population). In the United States, as of 2017, about 7% of people have used MDMA at some point in their lives and 0.9% have used it in the last year. The lethal risk from one dose of MDMA is estimated to be from 1 death in 20,000 instances to 1 death in 50,000 instances.