Meconium in the context of Defecate


Meconium in the context of Defecate

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⭐ Core Definition: Meconium

Meconium is the earliest stool of a mammalian infant resulting from defecation. Unlike later feces, meconium is composed of materials ingested during the time the infant spends in the uterus: intestinal epithelial cells, lanugo, mucus, amniotic fluid, bile, and water. Meconium, unlike later feces, is viscous and sticky like tar – its color usually being a very dark olive green and it is almost odorless. When diluted in amniotic fluid, it may appear in various shades of green, brown, or yellow. It should be completely passed by the end of the first few days after birth, with the stools progressing toward yellow (digested milk).

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Meconium in the context of Opium

Opium (also known as poppy tears, or Lachryma papaveris) is the dried latex obtained from the seed capsules of the opium poppy Papaver somniferum. Approximately 12 percent of opium is made up of the analgesic alkaloid morphine, which is processed chemically to produce heroin and other synthetic opioids for medicinal use and for the illegal drug trade. Opium's main psychoactive alkaloids, primarily morphine, act on μ-opioid receptors, causing analgesia and addiction with long-term use leading to tolerance, dependence, and increased cancer risk. The latex also contains the closely related opiates codeine and thebaine, and non-analgesic alkaloids such as papaverine and noscapine. The traditional, labor-intensive method of obtaining the latex is to scratch ("score") the immature seed pods (fruits) by hand; the latex leaks out and dries to a sticky yellowish residue that is later scraped off and dehydrated.

The English word for opium is borrowed from Latin, which in turn comes from Ancient Greek: ὄπιον (ópion), a diminutive of ὀπός (opós, "juice of a plant"). The word meconium (derived from the Greek for "opium-like", but now used to refer to newborn stools) historically referred to related, weaker preparations made from other parts of the opium poppy or different species of poppies. The Mediterranean region holds the earliest archaeological evidence of human use of opium poppies dating back to before 5000 BCE, with cultivation beginning around 3400 BCE in Mesopotamia. Opium was widely used for food, medicine, ritual, and as a painkiller throughout ancient civilizations including Greece, Egypt, and Islamic societies up to medieval times.

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Meconium in the context of Defecation

Defecation (or defaecation) follows digestion and is the necessary biological process by which organisms eliminate a solid, semisolid, or liquid waste material known as feces (or faeces) from the digestive tract via the anus or cloaca. The act has a variety of names, ranging from the technical (e.g. bowel movement), to the common (like pooping or crapping), to the obscene (shitting), to the euphemistic ("doing number two", "dropping a deuce" or "taking a dump"), to the juvenile ("going poo-poo" or "making doo-doo"). The topic, usually avoided in polite company, forms the basis of scatological humor.

Humans expel feces with a frequency varying from a few times daily to a few times weekly. Waves of muscular contraction (known as peristalsis) in the walls of the colon move fecal matter through the digestive tract towards the rectum. Flatus may also be expulsed. Undigested food may also be expelled within the feces, in a process called egestion. When birds defecate, they also expel urine and urates in the same mass, whereas other animals may also simultaneously urinate during defecation, but the processes are spatially separated. Defecation may also accompany childbirth and death. Babies defecate a unique substance called meconium prior to eating external foods.

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Meconium in the context of Meconium aspiration syndrome

Meconium aspiration syndrome (MAS), also known as neonatal aspiration of meconium, is a medical condition affecting newborn infants. It describes the spectrum of disorders and pathophysiology of newborns born in meconium-stained amniotic fluid (MSAF) and have meconium within their lungs. Therefore, MAS has a wide range of severity depending on what conditions and complications develop after parturition. Furthermore, the pathophysiology of MAS is multifactorial and extremely complex which is why it is the leading cause of morbidity and mortality in term infants.

The word meconium is derived from the Greek word mēkōnion meaning juice from the opium poppy as the sedative effects it had on the foetus were observed by Aristotle.

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