Margaret Burbidge in the context of California Institute of Technology

In astrophysics, stellar nucleosynthesis is the creation of chemical elements by nuclear fusion reactions within stars. Stellar nucleosynthesis has occurred since the original creation of hydrogen, helium and lithium during the Big Bang. As a predictive theory, it yields accurate estimates of the observed abundances of the elements. It explains why the observed abundances of elements change over time and why some elements and their isotopes are much more abundant than others. The theory was initially proposed by Fred Hoyle in 1946, who later refined it in 1954. Further advances were made, especially to nucleosynthesis by neutron capture of the elements heavier than iron, by Margaret and Geoffrey Burbidge, William Alfred Fowler and Fred Hoyle in their famous 1957 BFH paper, which became one of the most heavily cited papers in astrophysics history.

Stars evolve because of changes in their composition (the abundance of their constituent elements) over their lifespans, first by burning hydrogen (main sequence star), then helium (horizontal branch star), and progressively burning higher elements. However, this does not by itself significantly alter the abundances of elements in the universe as the elements are contained within the star. Later in its life, a low-mass star will slowly eject its atmosphere via stellar wind, forming a planetary nebula, while a higher–mass star will eject mass via a sudden catastrophic event called a supernova. The term supernova nucleosynthesis is used to describe the creation of elements during the explosion of a massive star or white dwarf.

Geoffrey Ronald Burbidge FRS (24 September 1925 – 26 January 2010) was an English astronomy professor and theoretical astrophysicist, most recently at the University of California, San Diego. He was married to astrophysicist Margaret Burbidge and was the second author of the influential BFH paper which she led.

The BFH paper was a landmark scientific paper on the origin of the chemical elements. The paper's title is Synthesis of the Elements in Stars, but it became known as BFH from the initials of its authors: Margaret Burbidge, Geoffrey Burbidge, William A. Fowler, and Fred Hoyle. It was written from 1955 to 1956 at the University of Cambridge and Caltech and published in Reviews of Modern Physics in 1957.

The BFH paper reviewed stellar nucleosynthesis theory and supported it with astronomical and laboratory data. It identified nucleosynthesis processes that are responsible for producing the elements heavier than iron and explained their relative abundances. The paper became highly influential in both astronomy and nuclear physics.

The Haute-Provence Observatory (OHP, French: Observatoire de Haute-Provence) is an astronomical observatory in the southeast of France, about 90 km east of Avignon and 100 km north of Marseille. It was established in 1937 as a national facility for French astronomers. Astronomical observations began in 1943 using the 1.20 m telescope, and the first research papers based on observations made at the observatory were published in 1944. Foreign observers first used the observatory in 1949, when Geoffrey and Margaret Burbidge visited.

The observatory lies at an altitude of about 650 m, on a plateau near the village of Saint-Michel-l'Observatoire in the Alpes-de-Haute-Provence département.