Madison County, Illinois in the context of "Southern Illinois"

Greater St. Louis is the 23rd-largest metropolitan statistical area (MSA) in the United States consisting with an MSA population more than 2.8 million, and almost 3 million CSA the largest in Missouri, and the second-largest in Illinois. Its core city—St. Louis, Missouri—sits in the geographic center of the metro area, on the west bank of the Mississippi River. The river bisects the metro area geographically between Illinois and Missouri, although the latter portion is much more populous. The MSA includes St. Louis County, which is independent of the City of St. Louis; their two populations are generally tabulated separately.

The St. Louis, MO-IL metropolitan statistical area (MSA) includes the City of St. Louis; the Illinois counties of Bond, Calhoun, Clinton, Jersey, Macoupin, Madison, Monroe, and St. Clair (known collectively as the Metro East); and the Missouri counties of Crawford (only the City of Sullivan), Franklin, Jefferson, Lincoln, St. Charles, St. Louis (separate from and not inclusive of the city of St. Louis), and Warren.

Cahokia is a settlement and former village in St. Clair County, Illinois, United States, founded as a colonial French mission in 1689. Cahokia is on the east side of the Mississippi River in the Greater St. Louis metropolitan area. As of the 2010 census, it had a population of 15,241. On May 6, 2021, the village was incorporated into the new city of Cahokia Heights.

The name refers to one of the clans of the historic Illiniwek confederacy, who met early French explorers to the region. Early European settlers named the nearby (and long-abandoned) Cahokia Mounds in present-day Madison County after the Illini clan. The UNESCO World Heritage Site and State Historic Park were developed by the Mississippian culture, active here from 900 to 1500 AD. A connection to the clan is possible but unknown. The area was part of an extensive urban complex, the largest of the far-flung Mississippian culture territory through the Mississippi and Ohio River Valleys.

Collinsville is a city located mainly in Madison County and partially in St. Clair County, Illinois, United States. As of the 2020 census, the city had a population of 24,366. Collinsville is approximately 14 miles (23 km) east of St. Louis, Missouri, and is part of that city's Metro East area.

Collinsville is the location of Cahokia Mounds State Historic Site, a National Historic Landmark and UNESCO World Heritage Site. This prehistoric urban complex is estimated to have had a population of thousands at its peak, long before European exploration in the area. The city is also known for the Brooks Catsup Bottle Water Tower, the world's largest ketchup bottle, and is billed as the world's horseradish capital.

Edwardsville is a city in Madison County, Illinois, United States, and its county seat. The population was 26,808 as of the 2020 census. The city was named in honor of Ninian Edwards, former governor of the Illinois Territory. Edwardsville is a part of Southern Illinois and the Metro East region within Greater St. Louis, located 18 miles (29 km) northeast of downtown St. Louis.

Southern Illinois University Edwardsville, the Edwardsville Arts Center, the Edwardsville Journal, the Madison County Record, and the Edwardsville Intelligencer are based in Edwardsville. Edwardsville High School and Metro-East Lutheran High School serve students in the area. Edwardsville also serves as the headquarters for Prairie Farms Dairy, one of the largest dairy cooperatives in the United States and ranked in the top 10 of the largest privately held companies in the St. Louis region. The city is part of the Edwardsville School District, which also includes the villages of Glen Carbon, Hamel and Moro, as well as the township areas around them.

Granite City is a city in Madison County, Illinois, United States, within the greater St. Louis metropolitan area. Its population was 27,549 at the 2020 census, making it the third-largest city in the Metro East and Southern Illinois regions, behind Belleville and O'Fallon. Officially founded in 1896, Granite City was named by the Niedringhaus brothers, William and Frederick, who established it as a steelmaking company town for the manufacture of graniteware kitchen utensils.

Alton (/ˈɔːltən/ AWL-tən) is a city on the Mississippi River in Madison County, Illinois, United States, about 18 miles (29 km) north of St. Louis, Missouri. The population was 25,676 at the 2020 census. It is a part of the River Bend area in the Metro-East region of the Greater St. Louis metropolitan area.

It is well known for its limestone bluffs along the river north of the city. It's the former location of an historical state penitentiary, and played a significant role preceding and during the American Civil War. It was the site of the last Abraham Lincoln and Stephen Douglas debate in October 1858. The former state penitentiary in Alton was used during the Civil War to hold up to 12,000 Confederate prisoners of war.

Godfrey is a village in Madison County, Illinois, United States. The population was 17,825 at the 2020 census. Godfrey is located within the River Bend portion of the Greater St. Louis metropolitan area.