The Lower Sava Valley (Slovene: Posavje, also Spodnje Posavje and Posavska regija) is a region in southeastern Slovenia on the border with Croatia. It has three major urban centres: Brežice, Krško, and Sevnica. Its borders are almost identical with those of the Lower Sava Statistical Region.
It extends along the lower part of the Sava River, from the town of Krško downstream to the international border. With an area of 885 km (4.4% of Slovenia) and a 2003 population of 70,262 (79 inhabitants per km in 409 settlements), it is Slovenia's second-smallest region and one of its least densely populated ones. The neighbouring regions are the Savinja region to the north, the Central Sava Valley (Slovene: Zasavje) to the west, and Lower Carniola to the south. The constituent municipalities are Krško, Brežice, Sevnica, Kostanjevica na Krki, Radeče, and Bistrica ob Sotli.