Lithium hydride in the context of Sodium hydride

A thermonuclear weapon, fusion weapon or hydrogen bomb (H-bomb) is a second-generation nuclear weapon, utilizing nuclear fusion. The most destructive weapons ever created, their yields typically exceed first-generation nuclear weapons by twenty times, with far lower mass and volume requirements. Characteristics of fusion reactions can make possible the use of non-fissile depleted uranium as the weapon's main fuel, thus allowing more efficient use of scarce fissile material. Its multi-stage design is distinct from the usage of fusion in simpler boosted fission weapons. The first full-scale thermonuclear test (Ivy Mike) was carried out by the United States in 1952, and the concept has since been employed by at least the five NPT-recognized nuclear-weapon states: the United States, Russia, the United Kingdom, China, and France.

The design of all thermonuclear weapons is believed to be the Teller–Ulam configuration. This relies on radiation implosion, in which X-rays from detonation of the primary stage, a fission bomb, are channelled to compress a separate fusion secondary stage containing thermonuclear fuel, primarily lithium-6 deuteride. During detonation, neutrons convert lithium-6 to helium-4 plus tritium. The heavy isotopes of hydrogen, deuterium and tritium, then undergo a reaction that releases energy and neutrons. For this reason, thermonuclear weapons are often colloquially called hydrogen bombs or H-bombs.