List of missions to the Moon in the context of "Exploration of the Moon"

Human spaceflight (also referred to as crewed spaceflight, or more historically manned spaceflight) is spaceflight with a crew or passengers aboard a spacecraft, often with the spacecraft being operated directly by the onboard human crew. Spacecraft can also be remotely operated from ground stations on Earth, or autonomously, without any direct human involvement. People trained for spaceflight are called astronauts (American or other), cosmonauts (Russian), or taikonauts (Chinese); and non-professionals are referred to as spaceflight participants or spacefarers.

The first human in space was Soviet cosmonaut Yuri Gagarin, who launched as part of the Soviet Union's Vostok program on 12 April 1961 at the beginning of the Space Race. On 5 May 1961, Alan Shepard became the first American in space, as part of Project Mercury. Humans traveled to the Moon nine times between 1968 and 1972 as part of the United States' Apollo program, and have had a continuous presence in space for 25 years and 30 days on the International Space Station (ISS). On 15 October 2003, the first Chinese taikonaut, Yang Liwei, went to space as part of Shenzhou 5, the first Chinese human spaceflight. As of December 2025, humans have not traveled beyond low Earth orbit since the Apollo 17 lunar mission in December 1972.

This is a list of active space probes which have escaped Earth orbit. It includes lunar space probes, but does not include space probes orbiting at the Sun–Earth Lagrangian points (for these, see List of objects at Lagrangian points). A craft is deemed "active" if it is still able to transmit usable data to Earth (regardless of whether it can receive commands).

The craft are further grouped by mission status – "en-route", "mission in progress" or "mission complete" – based on their primary mission. For example, though Voyager 1 is still contactable en-route to the Oort Cloud and has exited the Solar System, it is listed as "mission complete" because its primary task of studying Jupiter and Saturn has been accomplished. Once a probe has reached its first primary target, it is no longer listed as "en route" regardless of whether further travel is involved.

A moonbase (or lunar base) is a human outpost on or below the surface of the Moon. More than a mere site of activity or temporary camp, moonbases are extraterrestrial bases, supporting robotic or human activity, by providing surface infrastructure. Missions to the Moon have realized single-mission bases, (Tranquility Base being the first), as well as some small permanent infrastructure like lunar laser ranging installations.

Plans for establishing moonbases, with surface or sub-surface research stations, have been proposed and are actively pursued nationally and increasingly internationally. As of 2025, the two most advanced projects to set up moonbases have been pursued multilaterally as part of the US-led Artemis program, with its planned Artemis Base Camp and as the China-led International Lunar Research Station. A broader, international infrastructure has been envisioned with the so-called Moon Village concept, and a general international regulatory regime for lunar activity has been called for by the 1979 signed Moon Treaty, and advocated for with an implementation agreement since 2020.