Angelos in the context of "Despotate of Epirus"

Isaac II Angelos or Angelus (Greek: Ἰσαάκιος Κομνηνός Ἄγγελος, romanized: Isaákios Komnēnós Ángelos; September 1156 – 28 January 1204) was Byzantine Emperor from 1185 to 1195, and co-Emperor with his son Alexios IV Angelos from 1203 to 1204. In an 1185 revolt against the Emperor Andronikos Komnenos, Isaac seized power and rose to the Byzantine throne, establishing the Angelos family as the new imperial dynasty.

His father Andronikos Doukas Angelos was a military leader in Asia Minor (c. 1122 – aft. 1185) who married Euphrosyne Kastamonitissa (c. 1125 – aft. 1195). Andronikos Doukas Angelos was the son of Constantine Angelos and Theodora Komnene (b. 15 January 1096/1097), the youngest daughter of Emperor Alexios I Komnenos and Irene Doukaina. Thus Isaac was a member of the extended imperial clan of the Komnenoi.

Theodore Komnenos Doukas (Greek: Θεόδωρος Κομνηνὸς Δούκας, Theodōros Komnēnos Doukas; Latinized as Theodore Comnenus Ducas; died c. 1253) or Theodore Angelos Komnenos was the ruler of Epirus and Thessaly from 1215 to 1230 and of Thessalonica and most of Macedonia and western Thrace from 1224 to 1230. He was also the power behind the rule of his sons John and Demetrios over Thessalonica in 1237–1246.

Theodore was the scion of a distinguished Byzantine aristocratic family related to the imperial Komnenos, Doukas, and Angelos dynasties. Nevertheless, nothing is known about Theodore's life before the conquest of Constantinople and dissolution of the Byzantine Empire by the Fourth Crusade in 1204. Following the fall of Constantinople, he served Theodore I Laskaris, founder of the Empire of Nicaea, for a few years before being called to Epirus, where his half-brother Michael I Komnenos Doukas had founded an independent principality. When Michael died in 1215, Theodore sidelined his brother's underage and illegitimate son Michael II and assumed the governance of the Epirote state. Theodore continued his brother's policy of territorial expansion. Allied with Serbia, he expanded into Macedonia, threatening the Latin Kingdom of Thessalonica. The capture of the Latin Emperor Peter II of Courtenay in 1217 opened the way to the gradual envelopment of Thessalonica, culminating in the city's fall in 1224.

The House of Komnenos (pl. Komnenoi; Greek: Κομνηνός, pl. Κομνηνοί, pronounced [komniˈni]), Latinized as Comnenus (pl. Comneni), was a Byzantine Greek noble family who ruled the Byzantine Empire in the 11th and 12th centuries. The first reigning member, Isaac I Komnenos, ruled from 1057 to 1059. The family returned to power under Alexios I Komnenos in 1081 who established their rule for the following 104 years until it ended with Andronikos I Komnenos in 1185. In the 13th century, they founded the Empire of Trebizond, a Byzantine rump state which they ruled from 1204 to 1461. At that time, they were commonly referred to as Grand Komnenoi (Μεγαλοκομνηνοί, Megalokomnenoi), a style that was officially adopted and used by George Komnenos and his successors. Through intermarriages with other noble families, notably the Doukas, Angelos, and Palaiologos, the Komnenos name appears among most of the major noble houses of the late Byzantine world.

The House of Laskaris (Greek: Λάσκαρις (Láskaris), later Λάσκαρης; feminine form Laskarina; Greek: Λασκαρίνα), Latinized as Lascaris, was a Byzantine Greek noble family which rose to prominence during the late Byzantine period. The members of the family formed the ruling dynasty of the Empire of Nicaea, a Byzantine rump state that existed from the 1204 sack of Constantinople by the Fourth Crusade until the restoration of the Empire under the Palaeologan dynasty in 1261.

Upon the sack of the Byzantine capital by the Crusaders, Alexios V Doukas was overthrown and the Latin Empire was established in most of his former lands. Byzantine nobility would flee the Latin territories and establish the three independent Greek states that rivaled the Crusaders. After a successful resistance in Asia Minor, Theodore I Laskaris founded the Empire of Nicaea and laid claims to the Byzantine throne, along with the Angelos family of Epirus and the Komnenoi of Trebizond. The Byzantine Greek population of Asia Minor sought refuge to Theodore's empire, which gradually acquired control over much of western Anatolia. The empire was further strengthened after the military victories of Theodore's successor, John III Vatatzes. John's son, Theodore II Laskaris, maintained the empire's strength until the throne was passed to his underage son, John IV Laskaris. In 1259 John fell victim to an aristocratic conspiracy which managed to establish Michael Palaiologos as his regent and co-emperor.

The Byzantine Empire was ruled by emperors of the Angelos dynasty between 1185 and 1204 AD. The Angeloi rose to the throne following the deposition of Andronikos I Komnenos, the last male-line Komnenos to rise to the throne. The Angeloi were female-line descendants of the previous dynasty. While in power, the Angeloi were unable to stop the invasions of the Turks by the Sultanate of Rum, the uprising and resurrection of the Bulgarian Empire, and the loss of the Dalmatian coast and much of the Balkan areas won by Manuel I Komnenos to the Kingdom of Hungary.

Infighting among the elite saw Byzantium lose substantial financial capability and military power. The previous policies of openness with Western Europe, followed by the sudden massacre of Latins under Andronikos, had preceded the rule of the Angeloi making enemies among Western European states. The weakening of the empire under the Angeloi dynasty resulted in the partitioning of the Byzantine Empire when in 1204, soldiers of the Fourth Crusade overthrew the last Angeloi Emperor, Alexios V Doukas.

Euphrosyne Kastamonitissa (Greek: Εύφροσύνη Κασταμονίτισσα) was a Byzantine noblewoman of the Kastamonites family, a wife of Andronikos Doukas Angelos (a cousin of the ruling Komnenos dynasty) and mother of the two future Byzantine emperors from the Angelos family: Isaac II Angelos and Alexios III Angelos.