Inorganic ions in the context of Kidneys


Inorganic ions in the context of Kidneys

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⭐ Core Definition: Inorganic ions

Inorganic ions in animals and plants are ions necessary for vital cellular activity. In body tissues, ions are also known as electrolytes, essential for the electrical activity needed to support muscle contractions and neuron activation. They contribute to osmotic pressure of body fluids as well as performing a number of other important functions. Below is a list of some of the most important ions for living things as well as examples of their functions:

  • Ca – calcium ions are a component of bones and teeth. They also function as biological messengers, as do most of the ions listed below. (See Hypocalcaemia.)
  • Zn - zinc ions are found in very small concentrations in the body, and their main purpose is that of an antioxidant; the zinc ions act as antioxidants both generally and for liver specific pro-oxidants. Zinc ions can also act as an antioxidant-like stabilizer for some macro-molecules which bind zinc ions with high affinity, especially in cysteine-rich binding sites. These binding sites use these zinc ions as a stabilizer to protein folds, making these protein motifs more rigid in structure. These structures include zinc fingers, and have several different conformations.
  • K – potassium ions' main function in animals is osmotic balance, particularly in the kidneys. (See Hypokalemia.)
  • Na – sodium ions have a similar role to potassium ions. (See Sodium deficiency.)
  • Mn- manganese ions are seen being used as stabilizer for varying protein configurations. However, manganese ion overexposure is linked to several neurodegenerative diseases such as Parkinson's disease.
  • Mg – magnesium ions are a component of chlorophyll. (See Magnesium deficiency (plants))
  • Cl – inability to transport chloride ions in humans manifests itself as cystic fibrosis (CF)
  • CO
    3
     – the shells of sea creatures are calcium carbonate. In blood approximately 85% of carbon dioxide, is converted into aqueous carbonate ions (an acidic solution), allowing a greater rate of transportation.
  • Co- cobalt ions are present in the human body in amounts from 1 to 2 mg. Cobalt is observed in the heart, liver, kidney, and spleen, and considerably smaller quantities in the pancreas, brain, and serum. Cobalt is a necessary component of vitamin B12 and a fundamental coenzyme of cell mitosis. Cobalt is crucial for amino acid formation and some proteins to create myelin sheath in nerve cells. Cobalt also plays a role in creating neurotransmitters, which are vital for proper function within the organism.
  • PO
    4
     – adenosine triphosphate (ATP) is a common molecule which stores energy in an accessible form. Bone is calcium phosphate.
  • Fe/Fe – as found in haemoglobin, the main oxygen carrying molecule has a central iron ion.
  • NO
    3
     – source of nitrogen in plants for the synthesis of proteins.
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Inorganic ions in the context of Coenzyme

A cofactor is a non-protein chemical compound or metallic ion that is required for an enzyme's role as a catalyst (a catalyst is a substance that increases the rate of a chemical reaction). Cofactors can be considered "helper molecules" that assist in biochemical transformations. The rates at which these happen are characterized in an area of study called enzyme kinetics. Cofactors typically differ from ligands in that they often derive their function by remaining bound.

Cofactors can be classified into two types: inorganic ions and complex organic molecules called coenzymes. Coenzymes are mainly derived from vitamins and other organic essential nutrients in small amounts (some definitions limit the use of the term "cofactor" for inorganic substances; both types are included here).

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Inorganic ions in the context of Cofactor (biochemistry)

A cofactor is a non-protein chemical compound or metallic ion that is required for an enzyme's role as a catalyst. Cofactors can be considered "helper molecules" that assist in biochemical transformations. The rates at which these happen are characterized in an area of study called enzyme kinetics. Cofactors typically differ from ligands in that they often derive their function by remaining bound.

Cofactors can be classified into two types: inorganic ions and complex organic molecules called coenzymes. Coenzymes are mainly derived from vitamins and other organic essential nutrients in small amounts (some definitions limit the use of the term "cofactor" for inorganic substances; both types are included here).

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Inorganic ions in the context of Mucus

Mucus (/ˈmjkəs/, MEW-kəs) is a slippery aqueous secretion produced by, and covering, mucous membranes. It is typically produced from cells found in mucous glands, although it may also originate from mixed glands, which contain both serous and mucous cells. It is a viscous colloid containing inorganic salts, antimicrobial enzymes (such as lysozymes), immunoglobulins (especially IgA), and glycoproteins such as lactoferrin and mucins, which are produced by goblet cells in the mucous membranes and submucosal glands. Mucus covers the epithelial cells that interact with outside environment, serves to protect the linings of the respiratory, digestive, and urogenital systems, and structures in the visual and auditory systems from pathogenic fungi, bacteria and viruses. Most of the mucus in the body is produced in the gastrointestinal tract.

Amphibians, fish, snails, slugs, and some other invertebrates also produce external mucus from their epidermis as protection against pathogens, to help in movement, and to line fish gills. Plants produce a similar substance called mucilage that is also produced by some microorganisms.

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Inorganic ions in the context of Mitochondrial matrix

In the mitochondrion, the matrix is the space within the inner membrane. It can also be referred as the mitochondrial fluid. The word "matrix" stems from the fact that this space is viscous, compared to the relatively aqueous cytoplasm. The mitochondrial matrix contains the mitochondrial DNA, ribosomes, soluble enzymes, small organic molecules, nucleotide cofactors, and inorganic ions. The enzymes in the matrix facilitate reactions responsible for the production of ATP, such as the citric acid cycle, oxidative phosphorylation, oxidation of pyruvate, and the beta oxidation of fatty acids.

The composition of the matrix based on its structures and contents produce an environment that allows the anabolic and catabolic pathways to proceed favorably. The electron transport chain and enzymes in the matrix play a large role in the citric acid cycle and oxidative phosphorylation. The citric acid cycle produces NADH and FADH2 through oxidation that will be reduced in oxidative phosphorylation to produce ATP.

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