Iatrogenesis in the context of "Drug interaction"

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⭐ Core Definition: Iatrogenesis

Iatrogenesis is the causation of a disease, a harmful complication, or other ill effect by any medical activity, including diagnosis, intervention, error, or negligence. First used in this sense in 1924, the term was introduced to sociology in 1976 by Ivan Illich, alleging that industrialized societies impair quality of life by overmedicalizing life. Iatrogenesis may thus include mental suffering via medical beliefs or a practitioner's statements. Some iatrogenic events are obvious, like amputation of the wrong limb, whereas others, like drug interactions, can evade recognition. In a 2013 estimate, about 20 million negative effects from treatment had occurred globally. In 2013, an estimated 142,000 persons died from adverse effects of medical treatment, up from an estimated 94,000 in 1990.

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Iatrogenesis in the context of Adverse effect

An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery. An adverse effect may be termed a "side effect", when judged to be secondary to a main or therapeutic effect. The term complication is similar to adverse effect, but the latter is typically used in pharmacological contexts, or when the negative effect is expected or common. If the negative effect results from an unsuitable or incorrect dosage or procedure, this is called a medical error and not an adverse effect. Adverse effects are sometimes referred to as "iatrogenic" because they are generated by a physician/treatment. Some adverse effects occur only when starting, increasing or discontinuing a treatment.Using a drug or other medical intervention which is contraindicated may increase the risk of adverse effects. Adverse effects may cause complications of a disease or procedure and negatively affect its prognosis. They may also lead to non-compliance with a treatment regimen. Adverse effects of medical treatment resulted in 142,000 deaths in 2013 up from 94,000 deaths in 1990 globally.

The harmful outcome is usually indicated by some result such as morbidity, mortality, alteration in body weight, levels of enzymes, loss of function, or as a pathological change detected at the microscopic, macroscopic or physiological level. It may also be indicated by symptoms reported by a patient. Adverse effects may cause a reversible or irreversible change, including an increase or decrease in the susceptibility of the individual to other chemicals, foods, or procedures, such as drug interactions.

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Iatrogenesis in the context of Latent homosexuality

Latent homosexuality is an erotic attraction toward members of the same sex that is not consciously experienced or expressed in overt action. This may mean a hidden inclination or potential for interest in homosexual relationships, which is either suppressed or not recognized, and which has not yet been explored, or may never be explored.

The term was originally proposed by Sigmund Freud. Some argue that latent homosexuality is a potentially iatrogenic effect (that is, it is not present until suggested by a therapist). Others argue that the term latent is not truly applicable in the case of homosexual urges, since they are often not in the unconscious or unexpressed category, but rather exist in the conscious mind and are repressed on a conscious level.

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Iatrogenesis in the context of Medical error

A medical error is a preventable adverse effect of care ("iatrogenesis"), whether or not it is evident or harmful to the patient. This might include an inaccurate or incomplete diagnosis or treatment of a disease, injury, syndrome, behavior, infection, or other ailments.

The incidence of medical errors varies depending on the setting. The World Health Organization has named adverse outcomes due to patient care that is unsafe as the 14th causes of disability and death in the world, with an estimated 1/300 people may be harmed by healthcare practices around the world.

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Iatrogenesis in the context of Ivan Illich

Ivan Dominic Illich (/ɪˈvɑːn ˈɪlɪ/ iv-AHN IL-itch; German: [ˈiːvan ˈɪlɪtʃ]; 4 September 1926 – 2 December 2002) was an Austrian Catholic priest, theologian, philosopher, and social critic. His 1971 book Deschooling Society criticises modern society's institutional approach to education, an approach that demotivates and alienates individuals from the process of learning. His 1975 book Medical Nemesis, importing to the sociology of medicine the concept of medical harm, argues that industrialised society widely impairs quality of life by overmedicalising life, pathologizing normal conditions, creating false dependency, and limiting other more healthful solutions. Illich called himself "an errant pilgrim."

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Iatrogenesis in the context of Pneumothorax

A pneumothorax is collection of air in the pleural space between the lung and the chest wall. Symptoms typically include sudden onset of sharp, one-sided chest pain and shortness of breath. In a minority of cases, a one-way valve is formed by an area of damaged tissue, in which case the air pressure in the space between chest wall and lungs can be higher; this has been historically referred to as a tension pneumothorax, although its existence among spontaneous episodes is a matter of debate. This can cause a steadily worsening oxygen shortage and low blood pressure. This could lead to a type of shock called obstructive shock, which could be fatal unless reversed. Very rarely, both lungs may be affected by a pneumothorax. It is often called a "collapsed lung", although that term may also refer to atelectasis.

A primary spontaneous pneumothorax is one that occurs without an apparent cause and in the absence of significant lung disease. Its occurrence is fundamentally a nuisance. A secondary spontaneous pneumothorax occurs in the presence of existing lung disease. Smoking increases the risk of primary spontaneous pneumothorax, while the main underlying causes for secondary pneumothorax are COPD, asthma, and tuberculosis. A traumatic pneumothorax can develop from physical trauma to the chest (including a blast injury) or from a complication of a healthcare intervention.

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Iatrogenesis in the context of Dissociative identity disorder

Dissociative identity disorder (DID), previously known as multiple personality disorder (MPD), is characterized by the presence of at least two personality states or "alters". The diagnosis is controversial and remains disputed. Proponents of DID support the trauma model, viewing the disorder as an organic response to severe childhood trauma. Critics of the trauma model support the sociogenic (fantasy) model of DID as a societal construct and learned behavior used to express distress; developed through iatrogenesis in therapy, cultural beliefs, and exposure to the behavior in media or online.

Public perceptions of the disorder were popularized by alleged true stories in the 20th century; Sybil influenced many elements of the diagnosis, but was later found to be fraudulent. After multiple personality disorder (MPD) was recognized as a diagnosis in DSM-III in 1975, an epidemic of the disorder spread across North America, closely tied to the satanic panic. Therapists began using hypnosis on patients, believing they were discovering alters and recovering forgotten memories of satanic ritual abuse. Psychologists familiar with the malleability of memory argued they were constructing false memories. Diagnoses reached 50,000 by the 1990s, but the FBI failed to validate allegations made against caregivers. Skepticism increased when MPD patients recovered from the behavior, retracted their false memories, and brought successful lawsuits against therapists. A sharp decline in cases followed, and the disorder was reclassified as "dissociative identity disorder" (DID) in DSM-IV. In the 2020s, an uptick in DID cases followed the spread of viral videos about the disorder on TikTok and YouTube.

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