The Hull and Selby Railway is a railway line between Kingston upon Hull and Selby in the United Kingdom which was authorised by an act of Parliament in 1836 and opened in 1840. As built the line connected with the Leeds and Selby Railway (opened 1834) at Selby, with a Hull terminus adjacent to the Humber Dock.
A connection to Cottingham, Beverley, Driffield and Bridlington was made in 1846 with the opening of the Hull and Selby Railway (Bridlington Branch), now part of the Yorkshire Coast Line; a new 4+1⁄2-mile (7.2 km) route into Hull was opened in 1848, along with a new main station, Hull Paragon; a connection to Market Weighton from Barlby near Selby was made in 1848 (closed 1954, see Selby to Driffield Line); an urban branch line terminating in east Hull, the Victoria Dock Branch Line was opened in 1853 (closed 1968); a connection at Gilberdyke onto the Hull and Doncaster Railway passing via Goole was made in 1863; and in 1871 North Eastern Railway's York and Doncaster branch opened in 1871, with its northern half branching from the line towards York just east of Selby.