Health claim in the context of Cholesterol

Scientific consensus is the majority judgment and position by active, qualified experts in a specific scientific discipline to establish a conclusion or fact. Scientific consensus results from the self-correcting scientific process of peer review, replication of the event through the scientific method, scholarly debate, meta-analysis, and publication of high-quality review articles, monographs, or guidelines in reputable books and journals to establish facts and durable knowledge about the topic.

Reaching consensus requires significant scientific agreement among qualified experts, a process based on scientific substantiation of a claim that meets the burden of proof by proposing a possible cause-and-effect mechanism supported by the totality of evidence, leading to agreement among experts. In many countries, scientific consensus established on significant scientific agreement is the basis for regulatory approval of drugs to specify a health claim for the properties of the approved therapeutic agent.

Vitamin C (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits, berries and vegetables. It is also a generic prescription medication and in some countries is sold as a non-prescription dietary supplement. As a therapy, it is used to prevent and treat scurvy, a disease caused by vitamin C deficiency.

Vitamin C is an essential nutrient involved in the repair of tissue, the formation of collagen, and the enzymatic production of certain neurotransmitters. It is required for the functioning of several enzymes and is important for immune system function. It also functions as an antioxidant. Vitamin C may be taken by mouth or by intramuscular, subcutaneous or intravenous injection. Various health claims exist on the supposition that moderate vitamin C deficiency increases disease risk, such as for the common cold, cancer or COVID-19. There are also claims of benefits from vitamin C supplementation in excess of the recommended dietary intake for people who are not considered vitamin C deficient. Vitamin C is generally well tolerated. Large doses may cause gastrointestinal discomfort, headache, trouble sleeping, and flushing of the skin. The United States National Academy of Medicine recommends against consuming large amounts.