Hamza ibn Abd al-Muttalib in the context of "Amr ibn Hisham"

Sayyid is an honorific title of Hasanid and Husaynid lineage, recognized as descendants of the Islamic prophet Muhammad through his daughter Fatima and Ali's sons Hasan and Husayn. The title may also refer to the descendants of the family of the Bani Hashim through the Prophet's great-grandfather Hashim, and others including Hamza, Abbas, Abu Talib, and Asad ibn Hashim.

See also Sharif, which has a good description of three types of identification for that term and co-relates to this term. In its narrowest sense, a sayyid is a descendant of Husayn ibn Ali, but the term is also more generally used for descendants of The Prophet.

The Battle of Uhud (Arabic: غزوة أحد, romanized: Ghazwat ʾUḥud) was fought between the early Muslims and the Quraysh during the Muslim–Quraysh wars in a valley north of Mount Uhud near Medina on Saturday, 23 March 625 AD (7 Shawwal, 3 AH).

Following the Muslim emigration to Medina, hostilities with the Quraysh intensified, largely due to Muslim raids on Meccan trade caravans. In 624, the Quraysh suffered a major defeat at the Battle of Badr, during which several of their leaders were killed. The following year, Abu Sufyan ibn Harb led a force of approximately 3,000 men toward Medina to avenge the loss. The two sides met near Mount Uhud, just north of the city. At the outset of the engagement, the Muslims gained the upper hand and forced the Meccan lines to retreat. A group of Muslim archers had been stationed by Muhammad on a nearby hill in order to protect the army’s rear and guard against a cavalry attack. However, believing the battle was won, many of them left their positions to collect spoils from the Meccan camp. This lapse allowed the Meccan cavalry, led by Khalid ibn al-Walid, to launch a counterattack from the rear, reversing the momentum of the battle, and disrupting the Muslim lines. The resulting chaos led to heavy losses on the Muslim side, including the death of Hamza ibn Abd al-Muttalib.