Guaraní people in the context of Oriental Republic of Uruguay

During and after the European colonization of the Americas, European settlers practiced widespread enslavement of Indigenous peoples. In the 15th century, the Spanish introduced chattel slavery through warfare and the cooption of existing systems. A number of other European powers followed suit, and from the 15th through the 19th centuries, between two and five million Indigenous people were enslaved, which had a devastating impact on many Indigenous societies, contributing to the overwhelming population decline of Indigenous peoples in the Americas.

After the decolonization of the Americas, the enslavement of Indigenous peoples continued into the 19th century in frontier regions of some countries, notably parts of Brazil, Peru Northern Mexico, and the Southwestern United States. Some Indigenous groups adopted European-style chattel slavery during the colonial period, most notably the "Five Civilized Tribes" in the United States, however far more Indigenous groups were involved in the selling of Indigenous slaves to Europeans.

Paraguay (Guarani: Paraguái), officially the Republic of Paraguay, is a landlocked country located in the central region of South America. It borders Bolivia to the northwest and north, Brazil to the northeast and east, and Argentina to the southeast, south, and west. Paraguay has access to the Atlantic Ocean via the Paraná–Paraguay Waterway. The country is governed as a unitary presidential republic composed of a capital district and seventeen departments. Its capital and largest city is Asunción.

The indigenous Guaraní had been living in eastern Paraguay for at least a millennium before the arrival of Spanish conquistadores in 1524. The city of Asunción was founded in 1537 as the first capital of the Governorate of the Río de la Plata within the Spanish Empire. During the 17th century, Paraguay was the center of Jesuit missions, where the natives were converted to Christianity and introduced to European culture. After the expulsion of the Jesuits from Spanish territories in 1767, Paraguay increasingly became a peripheral colony. Following independence from Spain in the early 19th century, Paraguay was ruled by a series of authoritarian governments. This period ended with the disastrous Paraguayan War (1864–1870), during which the country lost half its prewar population and around 25–33% of its territory. In the 20th century, Paraguay faced another major international conflict—the Chaco War (1932–1935) against Bolivia—in which Paraguay prevailed. It subsequently came under a succession of military dictators, culminating in the 35-year regime of Alfredo Stroessner, which lasted until his overthrow in 1989 by an internal military coup. This marked the beginning of Paraguay's current democratic era.

Uruguay, officially the Oriental Republic of Uruguay, is a country in South America. It shares borders with Argentina to its west and southwest and Brazil to its north and northeast, while bordering the Río de la Plata to the south and the Atlantic Ocean to the southeast. It is part of the Southern Cone region of South America. Uruguay covers an area of approximately 176,215 square kilometers (68,037 sq mi). It has a population of almost 3.5 million people, of whom nearly 2 million live in the metropolitan area of its capital and largest city, Montevideo.

The area that became Uruguay was first inhabited by groups of hunter gatherers 13,000 years ago. The first European explorer to reach the region was Juan Díaz de Solís in 1516, but the area was colonized later than its neighbors. At the time of European arrival, the Charrúa were the predominant tribe, alongside other groups such as the Guaraní and the Chaná. However, none of these groups were socially or politically organized, which contributed to their decline. Amid territorial disputes, the Portuguese established Colônia do Sacramento in 1680, and the Spanish founded Montevideo as a military stronghold. Uruguay secured its independence between 1811 and 1828, following a four-way struggle involving Portugal, Spain, and later the United Provinces of the Río de la Plata and the Empire of Brazil. In 1830, the country enacted its constitution and was formally established as an independent state.

The Jesuit missions among the Guaraní were a type of settlement for the Guaraní people ("Indians" or "Indios") in an area straddling the borders of present-day Argentina, Brazil and Paraguay (the triple frontier). The missions were established by the Jesuit Order of the Catholic Church early in the 17th century and ended in the late 18th century after the expulsion of the Jesuit order from the Americas. The missions have been called an experiment in "socialist theocracy" or a rare example of "benign colonialism". Others have argued that "the Jesuits took away the Indians' freedom, forced them to radically change their lifestyle, physically abused them, and subjected them to disease".

In their newly acquired South American dominions, the Spanish and Portuguese Empires adopted a strategy of gathering native populations into communities called "Indian reductions" (Spanish: reducciones de indios, Portuguese: reduções). The objectives of the reductions were to impart Christianity and European culture. Secular as well as religious authorities created "reductions".

The Tupi people, a subdivision of the Tupi-Guarani linguistic families, were one of the largest groups of indigenous peoples in Brazil before its colonization. Scholars believe that while they first settled in the Amazon rainforest, from about 2,900 years ago the Tupi started to migrate southward and gradually occupied the Atlantic coast of Southeast Brazil.

Many Tupi people today are merged with the Guaraní people, forming the Tupi–Guarani languages. The Guarani languages are a subdivision of the Tupian languages.

Juan de Ayolas (died c. 1537) was a conquistador born in Briviesca who explored the watershed of the Río de la Plata for the Spanish Crown. He accompanied Pedro de Mendoza on his 1534 expedition to colonize the region between the Río de la Plata and the Strait of Magellan and briefly succeeded him as the second governor of the region after Mendoza returned home in 1537.

Seeking supplies, he sailed up the Paraná River and founded a fort called Corpus Christi, as Sebastian Cabot had before him. Leaving Domingo Martínez de Irala at Puerto la Candelaria (modern Fuerte Olimpo), he sailed up the Paraguay River seeking a connection to Peru. He fought with the Guaraní, crossed the Chaco to the Andes, and seized some loot there, but when he returned, he was killed with every man of his company by the Payagua.

Stevia (/ˈstiːviə, ˈstɛviə/) is a sweet sugar substitute that is about 50 to 300 times sweeter than sugar. It is extracted from the leaves of Stevia rebaudiana, a plant native to areas of Paraguay and Brazil. The active compounds in stevia are steviol glycosides (mainly stevioside and rebaudioside). Stevia is heat-stable, pH-stable, and not fermentable. Humans cannot metabolize the glycosides in stevia, and it therefore has zero calories. Its taste has a slower onset and longer duration than that of sugar, and at high concentrations some of its extracts may have an aftertaste described as licorice-like or bitter. Stevia is used in sugar- and calorie-reduced food and beverage products as an alternative for variants with sugar.

The plant Stevia rebaudiana has been used for centuries by the Guaraní peoples of South America, who called it ka'a he'ê ("sweet herb"). The leaves have been used traditionally for hundreds of years in both Paraguay and Brazil to sweeten local teas, and as a "sweet treat".

Mate (/ˈmɑːteɪ/ MAH-tay; Spanish: mate [ˈmate], Brazilian Portuguese: [ˈmatʃi]) is a traditional Paraguayan, Uruguayan, Argentine and Brazilian caffeine-rich infused herbal drink. It is also known as chimarrão in Portuguese, cimarrón in Spanish, and kaʼay in Guarani. It is made by soaking dried yerba mate (Ilex paraguariensis) leaves in hot water and is traditionally served with a metal straw (bombilla) in a container typically made from a calabash gourd (also called the mate), from water-resistant hardwoods such as Lapacho or Palo Santo, and also made from a cattle horn (guampa) in some areas. A very similar preparation, known as mate cocido, removes some of the plant material and sometimes comes in tea bags. Today, mate is also sold commercially in tea bags and as bottled iced tea.

Mate has been originally consumed by the Guaraní and Tupi peoples native to Paraguay, north-east of Argentina and South of Brazil. After European colonization, it was spread across the Southern Cone countries, namely Paraguay, Argentina, Uruguay and Chile, but it is also consumed in the South of Brazil and the Bolivian Chaco. Mate is the national beverage of Argentina, Paraguay and Uruguay. In Chile, mate is predominantly consumed in the central and southern regions. Mate is also popular in Lebanon and Syria, where it was brought by immigrants from Argentina.