Green Goblin in the context of "Spider-sense"

Spider-Man is a superhero in American comic books published by Marvel Comics. Created by writer-editor Stan Lee and artist Steve Ditko, he first appeared in the anthology comic book Amazing Fantasy #15 (August 1962) in the Silver Age of Comic Books. Considered one of the most popular and commercially successful superheroes, he has been featured in comic books, television shows, films, video games, novels, and plays.

Spider-Man is the secret identity of Peter Benjamin Parker, who was raised by his Aunt May and Uncle Ben in Queens, New York City, after the death of his parents. Lee, Ditko, and later writers had the character deal with the struggles of adolescence and young adulthood. Readers identified with his self-doubt and loneliness. Unlike previous teen heroes, Spider-Man was not a sidekick nor did he have a mentor. He would be given many supporting characters, such as his Daily Bugle boss J. Jonah Jameson; friends like Harry Osborn and Flash Thompson; romantic interests like Gwen Stacy, Mary Jane Watson, and the Black Cat; and enemies such as Doctor Octopus, the Green Goblin, and Venom. In his origin story, Peter gets his superhuman spider-powers and abilities after he was bitten by a radioactive spider. These powers include superhuman strength, speed, agility, reflexes and durability; clinging to surfaces and ceilings; and detecting danger with his precognitive "spider-sense". He sews a spider-web patterned spandex costume that fully covers his body and builds wrist-mounted "web-shooter" devices that shoot artificial spider-webs of his own design, which he uses for both fighting and "web swinging" across the city. Peter initially used his powers for personal gain, but after his Uncle Ben was killed by a burglar that he could have stopped but did not, he learned that "with great power comes great responsibility", and began to use his powers to fight crime as Spider-Man.

Marvel Comics is an American comic book publisher, a property of the Walt Disney Company since December 31, 2009, and a subsidiary of Disney Publishing Worldwide since March 2023. Marvel was founded in 1939 by Martin Goodman as Timely Comics, and by 1951 had generally become known as Atlas Comics. The Marvel era began in August 1961 with the launch of The Fantastic Four and other superhero titles created by Stan Lee, Jack Kirby, Steve Ditko, and numerous others. The Marvel brand, which had been used over the years and decades, was solidified as the company's primary brand.

Marvel counts among its characters such well-known superheroes as Spider-Man, Wolverine, Iron Man, Captain America, Hulk, Thor, Doctor Strange, Daredevil, Black Panther, and Captain Marvel, as well as popular superhero teams such as the Avengers, X-Men, Fantastic Four, and Guardians of the Galaxy. Its stable of well-known supervillains includes Doctor Doom, Magneto, Green Goblin, Venom, Red Skull, Loki, Ultron, Thanos, Apocalypse, and Galactus. Most of Marvel's fictional characters operate in a single reality known as the Marvel Universe, with most locations mirroring real-life places; many major characters are based in New York City. Additionally, Marvel has published several licensed properties from other companies. This includes Star Wars comics, twice from 1977 to 1987, and again since 2015.

Harold Theopolis Osborn is a character appearing in American comic books published by Marvel Comics, commonly in association with the superhero Spider-Man. Created by Stan Lee and Steve Ditko, the character first appeared in The Amazing Spider-Man #31 (December 1965).

Harry is the best friend of Peter Parker (Spider-Man's alter ego) and Flash Thompson, one of the ex-boyfriends of Mary Jane Watson, the son of Norman Osborn, the husband of Liz Allan and the father of Normie Osborn and Stanley Osborn. He is the second character to assume the Green Goblin alias while one of his clones was amongst the many users of the Iron Patriot armor as the superhero American Son. An artificial intelligence (A.I.) copy, known as the A.I. Harry Osborn, is also the creator of the clones Gabriel and Sarah who are both later revealed to be operating as his demonic revenant Kindred under the Harry A.I.'s command.

Gwendolyne Maxine "Gwen" Stacy is a character appearing in American comic books published by Marvel Comics, usually as a supporting character in those featuring Spider-Man (Peter Parker). A college student and the daughter of George and Helen Stacy, Gwen was the first romantic interest for Peter following his high school graduation before she was murdered by the Green Goblin (Norman Osborn). Her death has haunted Peter ever since, and stories published long afterwards indicate she still holds a special place in his heart.

Gwen was posthumously subjected to numerous cloning experiments by her former professor Miles Warren, Peter's clone Ben Reilly, and an A.I. of Harry Osborn, the latter resulting in the creation of the Kindreds, and Ben briefly resurrecting Gwen in "Dead No More: The Clone Conspiracy" (2016–2017), with the embodiment of Death herself confirming in Ben Reilly: The Scarlet Spider (2017–2018) that all clones Ben created of deceased people had their souls intact on being brought back, while clones of living people (like Ben himself) had unique souls of their own. A flashback solo miniseries, Gwen Stacy: Beyond Amazing (2020–2024), was written by Christos Gage. In The All-New, All-Deadly Gwenpool (2025), she is again resurrected with Weapon X-like abilities under the designation X-31, teaming up with Peter, isekai protagonist Gwen Poole, and archer Kate Bishop against "The Great Architect". In the alternate universes of Ultimate Marvel, Spider-Gwen, and Ultimate Spider-Man, a still-living Gwen becomes their respective realities' versions of Carnage, Spider-Woman, and Mysterio.

Spider-Man is a superhero created by Marvel Comics who debuted in the anthology comic book series issue Amazing Fantasy #15 (August 1962) during the Silver Age of Comics. After his debut, he received his own comic book entitled The Amazing Spider-Man. This comic introduced many of what would become his major supervillain adversaries. Spider-Man then became popular enough for more Spider-Man comic spinoffs (The Spectacular Spider-Man, Marvel Team-Up, Web of Spider-Man, Peter Parker: Spider-Man etc.) which introduced more recurring enemies of the web-slinger, across their various incarnations.

As with Spider-Man, most of his villains' powers originate from scientific accidents or the misuse of scientific technology. They can be classified into multiple categories, such as animal-themed villains (Doctor Octopus, Vulture, Black Cat, Lizard, Rhino, Scorpion, Kraven the Hunter, Jackal, Beetle, Kangaroo, Tarantula, and Puma), villains with powers over the elements (Sandman, Electro, Molten Man, and Hydro-Man), horror-themed villains (the Green Goblin, the Hobgoblin, Morbius, Morlun, and the Symbiotes), crime lords (the Kingpin, Tombstone, Hammerhead, Silvermane, and Mister Negative), inventors (the Shocker, the Tinkerer, Spencer Smythe, and Alistair Smythe), and masters of trickery and illusion (the Chameleon and Mysterio). There are, however, numerous villains that don't fit into any specific category, such as Mephisto, who originated as a Silver Surfer villain. The villains oftentimes form teams such as the Sinister Six to oppose the web-slinger.