A granulosa cell or follicular cell is a somatic cell of the sex cord that is closely associated with the developing female gamete (called an oocyte or egg) in the ovary of mammals.
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Granulosa cell in the context of Sexual differentiation
Sexual differentiation is the process of development of the sex differences between males and females from an undifferentiated zygote. Sex differentiation is usually distinct from sex determination; sex determination is the designation of the development stage towards either male or female, while sex differentiation is the pathway towards the development of the phenotype.
In many species, testicular or ovarian differentiation begins with the appearance of Sertoli cells in males and granulosa cells in females.
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