Gifu Prefecture (岐阜県, Gifu-ken; Japanese pronunciation: [ɡʲi.ɸɯ, ɡʲi.ɸɯ̥ꜜ.keɴ]) is a prefecture of Japan located in the Chūbu region of Honshu. Gifu Prefecture has a population of 2,040,000 (as of April 1, 2025) and has a geographic area of 10,621 square kilometres (4,101 sq mi). Gifu Prefecture borders Toyama Prefecture to the north; Ishikawa Prefecture to the northwest, Fukui Prefecture and Shiga Prefecture to the west, Mie Prefecture to the southwest, Aichi Prefecture to the south, and Nagano Prefecture to the east.
Gifu is the capital and largest city of Gifu Prefecture, with other major cities including Ōgaki, Kakamigahara, and Tajimi.