George E. Fox in the context of American Institute for Medical and Biological Engineering


George E. Fox in the context of American Institute for Medical and Biological Engineering

⭐ Core Definition: George E. Fox

George Edward Fox (born December 17, 1945) is an astrobiologist, a Professor Emeritus and researcher at the University of Houston. He is an elected fellow of the American Academy of Microbiology, the American Association for the Advancement of Science, American Institute for Medical and Biological Engineering and the International Astrobiology Society. Fox received his B.S. degree in 1967, and completed his Ph.D. degree in 1974; both in chemical engineering at Syracuse University.

From the Fall of 1973 until 1977, Fox was a research associate with Carl R. Woese at the University of Illinois at Urbana-Champaign. Their collaboration initially focused on 5S ribosomal RNA where they established the use of a comparative sequence approach to predict RNA secondary structure. Next, utilizing 16S ribosomal RNA finger printing technology developed in the Woese laboratory in large part by Mitchell Sogin, Fox and Woese discovered the third form of life now known as the Archaea.

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George E. Fox in the context of 16S ribosomal RNA

16S ribosomal RNA (or 16S rRNA) is the RNA component of the 30S subunit of a prokaryotic ribosome (SSU rRNA). It binds to the Shine-Dalgarno sequence and provides most of the SSU structure.

The genes coding for it are referred to as 16S rRNA genes and are used in reconstructing phylogenies, due to the slow rates of evolution of this region of the gene. Carl Woese and George E. Fox were two of the people who pioneered the use of 16S rRNA in phylogenetics in 1977. Multiple sequences of the 16S rRNA gene can exist within a single bacterium.

View the full Wikipedia page for 16S ribosomal RNA
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