Gens Claudia in the context of Appius Claudius Sabinus Regillensis

Germanicus Julius Caesar (24 May 15 BC – 10 October AD 19) was a Roman general and politician most famously known for his campaigns against Arminius in Germania. The son of Nero Claudius Drusus and Antonia the Younger, Germanicus was born into an influential branch of the patrician gens Claudia. The agnomen Germanicus was added to his full name in 9 BC when it was posthumously awarded to his father in honor of his victories in Germania. In AD 4 he was adopted by his paternal uncle Tiberius, himself the stepson and heir of Germanicus' great-uncle Augustus; ten years later, Tiberius succeeded Augustus as Roman emperor. As a result of his adoption, Germanicus became an official member of the gens Julia, another prominent family, to which he was related on his mother's side. His connection to the Julii Caesares was further consolidated through a marriage between him and Agrippina the Elder, a granddaughter of Augustus. He was also the father of Caligula, the maternal grandfather of Nero, and the older brother of Claudius.

During the reign of Augustus, Germanicus enjoyed an accelerated political career, entering the office of quaestor five years before the legal age in AD 7. He held that office until AD 9 where he was made praetor after the Pannonian war, and was elected consul for the first time in AD 12. The year after, he was made proconsul of Germania Inferior, Germania Superior, and all of Gaul. From there he commanded eight legions, about one-third of the entire Roman army at the time, which he led against the Germanic tribes in his campaigns from AD 14 to 16. He avenged the Roman Empire's defeat in the Teutoburg Forest and retrieved two of the three legionary eagles that had been lost during the battle. In AD 17, he returned to Rome, where he received a triumph before leaving to reorganize the provinces of Asia Minor, whereby he incorporated the provinces of Cappadocia and Commagene in AD 18.

Drusus Julius Caesar (7 October c. 14 BC – 14 September AD 23), also called Drusus the Younger, was the son of Emperor Tiberius, and heir to the Roman Empire following the death of his adoptive brother Germanicus in AD 19.

He was born at Rome to a prominent branch of the gens Claudia, the son of Tiberius and his first wife, Vipsania Agrippina. His name at birth was Nero Claudius Drusus after his paternal uncle Nero Claudius Drusus (Drusus the Elder). In AD 4, he assumed the name Julius Caesar following his father's adoption into the Julii by Augustus, and became Drusus Julius Caesar.

Publius Clodius Pulcher (c. 92 – 18 January 52 BC) was a Roman politician and demagogue. A noted opponent of Cicero, he was responsible during his plebeian tribunate in 58 BC for a massive expansion of the Roman grain dole as well as Cicero's exile from the city. Leader of one of the political mobs in the 50s, his political tactics – combining connections throughout the oligarchy with mass support from the poor plebs – made him a central player in the politics of the era.

Born to the influential patrician gens Claudia, he was embroiled early in his political career in a religious scandal which saw him develop a rivalry with the orator Cicero and become a plebeian in order to be eligible for the plebeian tribunate. He successfully stood as tribune of the plebs for 58 BC and passed six laws to restore Rome's collegia (private guilds and fraternities), expand the grain dole (making it free rather than subsidised while also using those collegia as means for distribution), annex Cyprus to pay for the dole, clarify augural law on religious obstruction, make it more difficult for the censors to expel senators from the senate, and exile Cicero for the unlawful execution of conspirators during the Catilinarian conspiracy.