Genetic isolate in the context of "Armenian highlands"

The Armenian highlands (Armenian: Հայկական լեռնաշխարհ, romanized: Haykakan leṙnašxarh; also known as the Eastern Anatolian highlands, Armenian upland, Armenian plateau, or Armenian tableland) comprise the most central and the highest of the three plateaus that together form the northern sector of West Asia. Clockwise starting from the west, the Armenian highlands are bounded by the Anatolian plateau, the Caucasus, the Kura-Aras lowlands, the Iranian Plateau, and Mesopotamia. The highlands are divided into western and eastern regions, defined by the Ararat Valley where Mount Ararat is located. Since the turn of the 20th century, Western Armenia has been relabeled as "Eastern Anatolia" by Ottoman and Turkish authorities. Eastern Armenia is part of Lesser Caucasus, which was historically known by some as the Anti-Caucasus, meaning "opposite of the Caucasus".

During the Iron Age, the region was known by variations of the name Ararat (Urartu, Uruatri, Urashtu). Later, the Highlands were known as Armenia Major, a central region to the history of Armenians, and one of the four geopolitical regions associated with Armenians, the other three being Armenia Minor, Sophene, and Commagene. The highlands are primarily defined by the geographical dispersal of its native inhabitants, the Armenians. Prior to the appearance of nominally Armenian people in historical records, historians have hypothesized that the region must have been home to various ethnic groups who became homogenous when the Armenian language came to prominence. The population of the Armenian highlands has had a high level of regional genetic continuity for over 6,000 years. Recent studies indicate that the Armenian people descend from the indigenous people of the Armenian highlands and form a distinct genetic isolate in the region. The region was also inhabited during Antiquity by minorities such as Assyrians, Georgians, Greeks, Jews, and Iranians. During the Middle Ages, Arabs and particularly Turkmens and Kurds settled in large numbers in the Armenian highlands.

In biological taxonomy, race is an informal rank in the taxonomic hierarchy for which various definitions exist. Sometimes it is used to denote a level below that of subspecies, while at other times it is used as a synonym for subspecies. It has been used as a higher rank than strain, with several strains making up one race. Races may be genetically distinct populations of individuals within the same species, or they may be defined in other ways, e.g. geographically, or physiologically. Genetic isolation between races is not complete, but genetic differences may have accumulated that are not (yet) sufficient to separate species.

The term is recognized by some, but not governed by any of the formal codes of biological nomenclature. Taxonomic units below the level of subspecies are not typically applied to animals.

Genetic studies of Jews are part of the population genetics discipline and are used to analyze the ancestry of Jewish populations, complementing research in other fields such as history, linguistics, archaeology, paleontology, and medicine. These studies investigate the origins of various Jewish ethnic divisions by using DNA to investigate whether different Jewish and non-Jewish populations have shared ancestry or not. The medical genetics of Jews are studied for population-specific diseases and disease commonalities with other ethnicities.

Studies on Jewish populations have been principally conducted using three types of genealogical DNA tests: autosomal (atDNA), mitochondrial (mtDNA), and Y-chromosome (Y-DNA). Autosomal testing, which looks at the largest sets of genes within peoples' DNA, shows that Jewish populations tended to form genetic isolates – relatively closely related groups in independent communities with most in a community sharing significant ancestry. The Ashkenazi Jews form the largest such group. Mitochondrial and Y-DNA tests look at maternal and paternal ancestry respectively, via two small groups of genes transmitted only via female or male ancestors.

The African palm civet (Nandinia binotata), also known as the two-spotted palm civet, is a small feliform mammal widely distributed in sub-Saharan Africa. It is listed as least concern on the IUCN Red List. It is the sole member of the superfamily Nandinioidea and the most genetically isolated carnivoran.