French Broad River in the context of Pisgah National Forest

The Tennessee River is a 652 mi (1,049 km) long river located in the southeastern United States . Flowing through the Tennessee Valley in the states of Tennessee, Alabama, Mississippi, and Kentucky, it begins at the confluence of French Broad and Holston rivers at Knoxville, and drains into the Ohio River near Paducah, Kentucky. It is the largest tributary of the Ohio, and drains a basin of 40,876 sq mi (105,870 km).

Its tributary, the Little Tennessee River, flows into it from Western North Carolina and northeastern Georgia.

The Holston River is a 136-mile (219 km) river that flows from Kingsport, Tennessee, to Knoxville, Tennessee. Along with its three major forks (North Fork, Middle Fork and South Fork), it comprises a major river system that drains much of northeastern Tennessee, southwestern Virginia, and northwestern North Carolina. The Holston's confluence with the French Broad River at Knoxville marks the beginning of the Tennessee River.

Asheville (/ˈæʃ.vɪl/ ASH-vill) is a city in Buncombe County, North Carolina, United States. Located at the confluence of the French Broad and Swannanoa rivers, it is the county seat of Buncombe County. It is the most populous city in Western North Carolina and the state's 11th-most populous city with a population of 94,589 at the 2020 census. The four-county Asheville metropolitan area has an estimated 422,000 residents.

Hot Springs is a town in Madison County, North Carolina, United States. The population was 520 at the 2020 census. It is part of the Asheville metropolitan statistical area. It is situated on the Appalachian Trail and French Broad River near the North Carolina-Tennessee border. Hot Springs is best known for its hiking trails, natural springs, and mountain town atmosphere.

Knox County is a county located in the U.S. state of Tennessee. The population was 506,748 as of a 2024 estimate, making it the third-most populous county in Tennessee. Its county seat is Knoxville, which is the third-most populous city in Tennessee. Knox County is included in the Knoxville metropolitan area. The county is located at the geographical center of the Great Valley of East Tennessee. Near the heart of the county is the origin of the Tennessee River, at the confluence of the Holston and French Broad rivers.