Epidemics in the context of "Novel pathogen"

The causes and mechanisms of the fall of the Western Roman Empire are a historical theme that was introduced by historian Edward Gibbon in his 1776 book The History of the Decline and Fall of the Roman Empire. Though Gibbon was not the first to speculate on why the empire collapsed, he was the first to give a well-researched and well-referenced account of the event, and started an ongoing historiographical discussion about what caused the fall of the Western Roman Empire. The traditional date for the end of the Western Roman Empire is 476 when the last Western Roman Emperor was deposed. Many theories of causality have been explored. In 1984, Alexander Demandt enumerated 210 different theories on why Rome fell, and new theories have since emerged. Gibbon himself explored ideas of internal decline (civil wars, the disintegration of political, economic, military, and other social institutions) and of attacks from outside the empire.

Many historians have postulated reasons for the collapse of the Western Roman Empire. Their conclusions usually belong in two broad schools: (1) external factors, such as military threats and barbarian invasions or (2) internal factors, such as a decline in "civic virtue" and military and economic capability. Most historians believe that the fall was due to a combination of both internal and external factors, but come down more heavily on one or the other as the most important cause of the fall. Modern scholarship has introduced additional factors such as climate change, epidemic diseases, and environmental degradation as important reasons for the decline. Some historians have postulated that the Roman Empire did not fall at all, but that the "decline" was instead a gradual, albeit often violent, transformation into the societies of the Middle Ages.

Medical microbiology, the large subset of microbiology that is applied to medicine, is a branch of medical science concerned with the prevention, diagnosis and treatment of infectious diseases. In addition, this field of science studies various clinical applications of microbes for the improvement of health. There are four kinds of microorganisms that cause infectious disease: bacteria, fungi, parasites and viruses, and one type of infectious protein called prion.

A medical microbiologist studies the characteristics of pathogens, their modes of transmission, mechanisms of infection and growth. The academic qualification as a clinical/Medical Microbiologist in a hospital or medical research centre generally requires a Bachelors degree while in some countries a Masters in Microbiology along with Ph.D. in any of the life-sciences (Biochem, Micro, Biotech, Genetics, etc.). Medical microbiologists often serve as consultants for physicians, providing identification of pathogens and suggesting treatment options. Using this information, a treatment can be devised.Other tasks may include the identification of potential health risks to the community or monitoring the evolution of potentially virulent or resistant strains of microbes, educating the community and assisting in the design of health practices. They may also assist in preventing or controlling epidemics and outbreaks of disease.Not all medical microbiologists study microbial pathology; some study common, non-pathogenic species to determine whether their properties can be used to develop antibiotics or other treatment methods.

In epidemiology, an outbreak is a sudden increase in occurrences of a disease when cases are in excess of normal expectancy for the location or season. It may affect a small and localized group or impact upon thousands of people across an entire continent. The number of cases varies according to the disease-causing agent, and the size and type of previous and existing exposure to the agent. Outbreaks include many epidemics, which is a term normally only used for infectious diseases, as well as diseases with an environmental origin, such as a water or foodborne disease. They may affect a region in a country or a group of countries. Pandemics are near-global disease outbreaks when multiple and various countries around the Earth are soon infected.

The miasma theory (also called the miasmic theory) is an abandoned medical theory that held that diseases—such as cholera, chlamydia, or plague—were caused by a miasma (μίασμα, Ancient Greek for pollution), a noxious form of "bad air", also known as night air. The theory held that epidemics were caused by miasma, emanating from rotting organic matter. Though miasma theory is typically associated with the spread of contagious diseases, some academics in the early 19th century suggested that the theory extended to other conditions, as well, e.g. one could become obese by inhaling the odor of food.

The miasma theory was advanced by Hippocrates in the fifth century BC and accepted from ancient times in Europe and China. The theory was eventually abandoned by scientists and physicians after 1880, replaced by the germ theory of disease; specific germs, not miasma, caused specific diseases. However, cultural beliefs about getting rid of odor made the clean-up of waste a high priority for cities. It also encouraged the construction of well-ventilated hospital facilities, schools, and other buildings.

The Catawba, also known as Issa, Essa or Iswä but most commonly Iswa (Catawba: Ye Iswąˀ 'people of the river'), are a federally recognized tribe of Native Americans, known as the Catawba Indian Nation. Their current lands are in South Carolina, on the Catawba River, near the city of Rock Hill. Their territory once extended into North Carolina, as well, and they still have legal claim to some parcels of land in that state. They were once considered one of the most powerful Southeastern tribes in the Carolina Piedmont, as well as one of the most powerful tribes in the South as a whole, with other, smaller tribes merging into the Catawba as their post-contact numbers dwindled due to the effects of colonization on the region.

The Catawba were among the East Coast tribes who made selective alliances with some of the early European colonists, when these colonists agreed to help them in their ongoing conflicts with other tribes. These were primarily the tribes of different language families: the Iroquois, who ranged south from the Great Lakes area and New York; the Algonquian Shawnee and Lenape (Delaware); and the Iroquoian Cherokee, who fought for control over the large Ohio Valley (including what is in present-day West Virginia). During the American Revolutionary War the Catawba supported the American colonists against the British. Decimated by colonial smallpox epidemics, warfare and cultural disruption, the Catawba declined markedly in number in the late eighteenth and nineteenth centuries. Some Catawba continued to live in their homelands in South Carolina, while others joined the Choctaw or Cherokee, at least temporarily.