Echigo Province in the context of Iwashiro Province

Nagao Kagetora (長尾 景虎; February 18, 1530 – April 19, 1578), later known as Uesugi Kenshin (上杉 謙信), was a Japanese daimyō (magnate). He was born in Nagao clan, and after adoption into the Uesugi clan, ruled Echigo Province in the Sengoku period of Japan. He was one of the most powerful daimyō of the Sengoku period. Known as the "Dragon of Echigo", while chiefly remembered for his prowess on the battlefield as a military genius and war hero, Kenshin is also regarded as an extremely skillful administrator who fostered the growth of local industries and trade, as his rule saw a marked rise in the standard of living of Echigo.

Kenshin is famed for his honourable conduct, his military expertise, a long-standing rivalry with Takeda Shingen, his numerous defensive campaigns to restore order in the Kantō region as the Kanto Kanrei, and his belief in the Buddhist god of war Bishamonten. Many of his followers and others believed him to be the avatar of Bishamonten and called Kenshin the "God of War".

The Battles of Kawanakajima (川中島の戦い, Kawanakajima no tatakai) were a series of battles fought in the Sengoku period of Japan between Takeda Shingen of Kai Province and Uesugi Kenshin of Echigo Province from 1553 to 1564. Shingen and Kenshin contested each other for control of the plain of Kawanakajima between the Sai River and Chikuma River in northern Shinano Province, located in the present-day city of Nagano. The battles were triggered after Shingen conquered Shinano, expelling Ogasawara Nagatoki and Murakami Yoshikiyo, who subsequently turned to Kenshin for help.

Five major battles of Kawanakajima occurred: Fuse in 1553, Saigawa in 1555, Uenohara in 1557, Hachimanbara in 1561, and Shiozaki in 1564. The most famous and severe battle was fought on 18 October 1561 in the heart of the Kawanakajima plain, thus being known the Battle of Kawanakajima. The battles were ultimately inconclusive and neither Shingen nor Kenshin established their control over the plain of Kawanakajima.

Shinano Province (信濃国, Shinano no Kuni; Japanese pronunciation: [ɕiꜜ.na.no (no kɯ.ɲi), ɕi.na.noꜜ-]) or Shinshū (信州; [ɕiꜜɰ̃.ɕɯː]) is an old province of Japan that is now Nagano Prefecture.

Shinano bordered Echigo, Etchū, Hida, Kai, Kōzuke, Mikawa, Mino, Musashi, Suruga, and Tōtōmi Provinces. The ancient capital was located near modern-day Matsumoto, which became an important city of the province.

Dewa Province (出羽国, Dewa no Kuni; Japanese pronunciation: [deꜜ.wa (no kɯ.ɲi)]) was a province of Japan comprising modern-day Yamagata Prefecture and Akita Prefecture, except for the city of Kazuno and the town of Kosaka. Dewa bordered on Mutsu and Echigō Provinces. Its abbreviated form name was Ushū (羽州).

Kōzuke Province (上野国, Kōzuke no Kuni; Japanese pronunciation: [koꜜː.(d)zɯ.ke (no kɯ.ɲi)]) was a province of Japan in the area of Japan that is today Gunma Prefecture. Kōzuke bordered Echigo, Shinano, Musashi and Shimotsuke Provinces. Its abbreviated form name was Jōshū (上州; [dʑoꜜː.ɕɯː]). Under the Engishiki classification system, Kōzuke was ranked as one of the 13 "great countries" (大国) in terms of importance, and one of the 30 "far countries" (遠国) in terms of distance from the imperial capital, Kyoto. The provincial capital is located in what is now the city of Maebashi; however, its exact location remains uncertain. The ichinomiya of the province is located in what is now the city of Tomioka.

Etchū Province (越中国, Etchū no Kuni; Japanese pronunciation: [eꜜt.tɕɯː (no kɯ.ɲi), et.tɕɯꜜː-]) was a province of Japan in the area that is today Toyama Prefecture in the Hokuriku region of Japan. Etchū bordered on Noto and Kaga Provinces to the west, Shinano and Hida Provinces to the south, Echigo Province to the east and the Sea of Japan to the north. Its abbreviated form name was Esshū (越州).

The Shinetsu Main Line (Japanese: 信越本線, Hepburn: Shin'etsu-honsen) is a railway line, consisting of three geographically separated sections, operated by the East Japan Railway Company (JR East) in Japan. It was originally one continuous line connecting Takasaki and Niigata via Nagano. Since the opening and later extension of the Hokuriku Shinkansen, sections running in parallel have either been discontinued or transferred to third-sector railway companies.

The name of the line refers to the old names for Nagano and Niigata prefectures, Shinano (Japanese: 信濃), and Echigo (Japanese: 越後).