Disinhibition in the context of "Psychoactive substances"

A violent crime, violent felony, crime of violence or crime of a violent nature is a crime in which an offender or perpetrator uses or threatens to use harmful force upon a victim. This entails both crimes in which the violent act is the objective, such as murder, assault, rape and assassination, as well as crimes in which violence is used as a method of coercion or show of force, such as robbery, extortion and terrorism. Violent crimes may, or may not, be committed with weapons. Depending on the jurisdiction, violent crimes may be regarded with varying severities, ranging from harassment, manslaughter, to murder.

Violent criminals who use hostile acts towards others include killers, active shooters, kidnappers, robbers, sex offenders, burglars, arsonists and torturers. Another category of violent criminals are pirates and hijackers of cars or aircraft. Criminal organizations, gangsters and drug cartels frequently employ violent criminals in their group, usually as enforcers or hitmen. Violent criminals often display characteristics such as low anger threshold, disinhibition/absence of impulsivity control, strong dominance/territorial instinct, antisocial personality, psychological/mental health issues and aggressive tendencies which enable them to carry out usually violent acts.

Frontotemporal dementia (FTD), also called frontotemporal degeneration disease or frontotemporal neurocognitive disorder, encompasses several types of dementia involving the progressive degeneration of the brain's frontal and temporal lobes. Men and women appear to be equally affected. FTD generally presents as a behavioral or language disorder with gradual onset. Signs and symptoms tend to appear in mid adulthood, typically between the ages of 45 and 65, although it can affect people younger or older than this. As of 2017 there is no cure or approved symptomatic treatment for FTD, although some off-label drugs and behavioral methods are prescribed.

Features of FTD were first described by Arnold Pick between 1892 and 1906. The name Pick's disease was coined in 1922, but is reserved for the behavioral variant of FTD, in which characteristic Pick bodies and Pick cells are present. These were first described by Alois Alzheimer in 1911. Common signs and symptoms include significant changes in social and personal behavior, disinhibition, apathy, blunting and dysregulation of emotions, and deficits in both expressive and receptive language.

Hypomania (literally "under mania" or "less than mania") is a psychiatric behavioral syndrome characterized essentially by an apparently non-contextual elevation of mood (i.e., euphoria) that contributes to persistently disinhibited behavior.

The individual with the condition may experience irritability, not necessarily less severe than full mania; the presence of marked irritability is a documented feature of hypomanic and mixed episodes in bipolar II disorder. According to DSM-5 criteria, hypomania is distinct from mania in that there is no significant functional impairment; mania, by DSM-5 definition, does include significant functional impairment and may have psychotic features.