Daniel Kirkwood (September 27, 1814 – June 11, 1895) was an American astronomer.
Kirkwood was born in Harford County, Maryland, to John and Agnes (née Hope) Kirkwood. He graduated in mathematics from the York County Academy in York, Pennsylvania, in 1838. After teaching there for five years, he became Principal of the Lancaster High School in Lancaster, Pennsylvania, and after another five years he moved on to become Principal of the Pottsville Academy in Pottsville, Pennsylvania. In 1851, he was elected as a member to the American Philosophical Society. The same year he became Professor of Mathematics at Delaware College and in 1856 Professor of Mathematics at Indiana University in Bloomington, Indiana, where he stayed until his retirement in 1886, with the exception of two years, 1865–1867, at Jefferson College in Canonsburg, Pennsylvania.