Cordillera Central (Puerto Rico) in the context of "Aibonito, Puerto Rico"

The Ponce metropolitan area (Spanish: área metropolitana de Ponce), is the second largest metropolitan statistical area (MSA) in Puerto Rico, comprising the municipalities of Ponce, Juana Díaz, Yauco, Villalba, Peñuelas, Adjuntas, and Guayanilla between the coastal plain and the Cordillera Central mountain subrange in the south central region of the main island. One of 6 metropolitan statistical areas in Puerto Rico, it lies within the Ponce–Coamo combined statistical area (CSA), which is one of 3 primary statistical areas in the main island as defined by the United States Census Bureau. As of 2023, census estimates place the population of the Ponce metropolitan area at 266,237.

Ciales (Spanish pronunciation: [ˈsjales], locally [ˈsjaleʔ]) is a town and municipality of Puerto Rico, located on the Central Mountain Range, northwest of Orocovis; south of Florida and Manatí; east of Utuado and Jayuya; and west of Morovis. Ciales is spread over eight barrios and Ciales Pueblo (the downtown area and the administrative center of the city). It is part of the San Juan-Caguas-Guaynabo Metropolitan Statistical Area.

Caguas (Spanish pronunciation: [ˈkaɣwas], locally [ˈkawaʔ]) is a city and municipality in central eastern Puerto Rico. Located in the eponymous Caguas Valley between the Sierra de Cayey and Sierra de Luquillo of the Central Mountain Range, it is bordered by San Juan and Trujillo Alto to the north, Gurabo and San Lorenzo to the west, Aguas Buenas, Cidra and Cayey to the east, and Patillas to the south. With a population of 127,244 as of the 2020 census, Caguas is the fifth most populated municipality in the archipelago and island and a principal city of the San Juan metropolitan area.

Since 2009, Caguas is the only municipality in Puerto Rico recognized as a Tree City USA by the Arbor Day Foundation.

List of rivers in Puerto Rico (U.S. Commonwealth), sorted by drainage basin and then alphabetically. There are 47 main rivers and 24 lagoons or reservoirs.

Most of Puerto Rico's rivers originate in the Cordillera Central. There are four slopes through which rainwater flows towards the sea. According to their orientation they are known as the north or Atlantic slope; southern slope or the Caribbean Sea; the east slope of the Virgin Passage and the Sonda de Vieques and the west slope or the Mona Passage. Due to the generally abundant rain and the flow of its water currents, the most important rivers of Puerto Rico slide down the north slope. Taíno and native people normally built their communities near the rivers. During the Spanish colonization era, the same was true with many pueblos being founded near rivers.

Utuado (Spanish pronunciation: [uˈtwaðo]) is a town and municipality of Puerto Rico located in the central mountainous region of the island known as the Cordillera Central. It is located north of Adjuntas and Ponce; south of Hatillo and Arecibo; east of Lares; and west of Ciales and Jayuya. It is the third-largest municipality in land area in Puerto Rico (after Arecibo and Ponce). According to the 2020 US Census, the municipality has a population of 28,287 spread over 24 barrios and Utuado pueblo (the downtown area and the administrative center of the city).

Utuado is the main municipality of the Utuado micropolitan statistical area and is part of the San Juan-Caguas-Fajardo Combined Statistical Area.

Jayuya (Spanish pronunciation: [xaˈʝuʝa]) is a town and municipality of Puerto Rico located in the mountainous center region of the island, north of Ponce; east of Utuado; and west of Ciales. Jayuya is spread over 10 barrios and Jayuya Pueblo (the downtown and administrative center of the city). It is the principal city of the Jayuya Micropolitan Statistical Area.

Named after the Taíno tribal leader, Hayuya, Jayuya is known for its skilled wood carvers. Among its monuments are the statue of Nemesio Canales and the bust of Hayuya, both by the Puerto Rican sculptor Tomás Batista.

The Mayagüez metropolitan area (Spanish: área metropolitana de Mayagüez), is the fourth largest metropolitan statistical area (MSA) in Puerto Rico, comprising the municipalities of Mayagüez, Cabo Rojo, San Germán, Lajas, Sabana Grande, and Hormigueros between the coastal plains and the Cordillera Central mountain subrange in the southwestern region of the main island. One of 6 metropolitan statistical areas in Puerto Rico, it lies within the Mayagüez–Aguadilla combined statistical area (CSA), which is one of 3 primary statistical areas in the main island as defined by the United States Census Bureau. As of 2023, census estimates place the population of the Mayagüez metropolitan area at 207,877.

Aguas Buenas (Spanish pronunciation: [ˈaɣwas ˈβwenas], locally [awaʔ ˈβwenaʔ]), popularly known as "La Ciudad de las Aguas Claras" or "The City of Clear Waters", is a town and municipality of Puerto Rico located in the Central Mountain Range, north of Cidra, south of Bayamón, Guaynabo and San Juan; east of Comerio; and north-west of Caguas. Aguas Buenas is spread over 9 barrios and Aguas Buenas Pueblo (the downtown area and the administrative center of the city). It is part of the San Juan-Caguas-Guaynabo Metropolitan Statistical Area.

The Caguas Valley (Spanish: Valle de Caguas), or the Caguas-Juncos Valley, and popularly referred to as the Turabo Valley (Valle del Turabo), is a large valley lying between two mountain subranges of the Cordillera Central, Sierra de Cayey and Sierra de Luquillo, in the eastern region of the main island of Puerto Rico. From west to east, the valley is concentrated in the municipalities of Caguas, Gurabo, San Lorenzo, Juncos, Las Piedras, and Humacao.