Complex partial seizure in the context of Parietal lobe


Complex partial seizure in the context of Parietal lobe

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⭐ Core Definition: Complex partial seizure

Focal seizures are seizures that originate within brain networks limited to one hemisphere of the brain. In most cases, each seizure type has a consistent site of onset and characteristic patterns of spread, although some individuals experience more than one type of focal seizure arising from distinct networks. Seizure activity may remain localized or propagate to the opposite hemisphere. Symptoms will vary according to where the seizure occurs. When seizures occur in the frontal lobe, the patient may experience a wave-like sensation in the head. When seizures occur in the temporal lobe, a feeling of déjà vu may be experienced. When seizures are localized to the parietal lobe, a numbness or tingling may occur. With seizures occurring in the occipital lobe, visual disturbances or hallucinations have been reported. Some focal seizures begin with an aura — a subjective experience that precedes or constitutes the seizure itself, particularly in focal preserved consciousness seizures.

Under the 2025 classification of the International League Against Epilepsy (ILAE), focal seizures are divided into three types: those with preserved consciousness, those with impaired consciousness, and those that evolve to bilateral tonic–clonic activity. Historically known as "partial seizures," focal seizures were previously subdivided into "simple partial" (preserved consciousness) and "complex partial" (impaired consciousness). These terms have been deprecated in favor of biologically grounded terminology aligned with advances in neurophysiology and imaging.

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Complex partial seizure in the context of Automatic behavior

Automatism is a set of brief unconscious or automatic behaviors, typically at least several seconds or minutes, while the subject is unaware of actions. This type of automatic behavior often occurs in certain types of epilepsy, such as complex partial seizures in those with temporal lobe epilepsy, or as a side effect of particular medications such as zolpidem.

Automatic behaviors involve the spontaneous production of purposeless verbal or motor behavior without conscious self-control or self-censorship. This condition can be observed in a variety of contexts, including schizophrenia, dissociative fugue, Tourette syndrome, epilepsy (in complex partial seizures and Jacksonian seizures), narcolepsy, or in response to a traumatic event.

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Complex partial seizure in the context of Status epilepticus

Status epilepticus (SE), or status seizure, is a medical condition characterized by a prolonged period of seizure activity without a complete return to normal. It is a medical urgency that can lead to irreversible brain injury if untreated.

Convulsive status epilepticus, the most dangerous and life-threatening type, is characterized by seizures of the tonic–clonic type, with a regular pattern of contraction and extension of the arms and legs, lasting at least 5 minutes without return to normal (time point 1). Early treatment is essential to minimize damage to the brain, which starts to particularly accrue after 30 minutes (time point 2). Status epilepticus may also be non-convulsive, manifesting in the form of absence seizures or complex partial seizures. For other seizure types, the time points may vary. Previous definitions used a 30-minute time limit irrespective of type of seizure.

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