Comma (music) in the context of "Tuning system"

In music theory, a comma is a very small interval, the difference resulting from tuning one note two different ways. Traditionally, there are two most common commata; the syntonic comma (80:81), "the difference between a just major 3rd and four just perfect 5ths less two octaves", and the Pythagorean comma (524288:531441, approximately 73:74), "the difference between twelve 5ths and seven octaves". The word comma used without qualification refers to the syntonic comma, which can be defined, for instance, as the difference between an F♯ tuned using the D-based Pythagorean tuning system, and another F♯ tuned using the D-based quarter-comma meantone tuning system. Pitches separated by either comma are considered the same note because conventional notation does not distinguish Pythagorean intervals from 5-limit intervals. Other intervals are considered commas because of the enharmonic equivalences of a tuning system. For example, in 53 TET, the harmonic seventh B♭ and A♯ are both approximated by the same interval although they are a septimal kleisma apart.