Coca in the context of "Herbal tea"

The Andean civilizations were South American complex societies of many indigenous people. They stretched down the spine of the Andes for 4,000 km (2,500 miles) from southern Colombia, to Ecuador and Peru, including the deserts of coastal Peru, to north Chile and northwest Argentina. Archaeologists believe that Andean civilizations first developed on the narrow coastal plain of the Pacific Ocean. The Caral or Norte Chico civilization of coastal Peru is the oldest known civilization in the Americas, dating back to 3500 BCE. Andean civilizations are one of at least five civilizations in the world deemed by scholars to be "pristine." The concept of a "pristine" civilization refers to a civilization that has developed independently of external influences and is not a derivative of other civilizations.

Despite the severe environmental challenges of high mountains and hyper-arid desert, the Andean civilizations domesticated a wide variety of crops, some of which, such as potatoes, peppers, peanuts, manioc, chocolate, and coca, became of worldwide importance. The Andean civilizations were noteworthy for monumental architecture, an extensive road system, textile weaving, and many unique characteristics of the societies they created.

Cocaine is a central nervous system stimulant and tropane alkaloid derived primarily from the leaves of two coca species native to South America: Erythroxylum coca and E. novogranatense. Coca leaves are processed into cocaine paste, a crude mix of coca alkaloids from which cocaine base is isolated and converted to cocaine hydrochloride. Cocaine was once a standard topical medication as a local anesthetic with intrinsic vasoconstrictor activity, but its high abuse potential, adverse effects, and cost have limited its use and led to its replacement by other medicines.

Street cocaine is commonly snorted, injected, or smoked as crack cocaine, with effects lasting up to 90 minutes depending on the route. Cocaine acts pharmacologically as a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI), producing reinforcing effects such as euphoria, increased alertness, concentration, libido, and reduced fatigue and appetite.

The illegal drug trade in Peru includes the growing of coca and the shipment of cocaine to the United States. In an example of the balloon effect, dramatic falls in coca cultivation in the late 1990s saw cultivation move to Colombia.

Juan Evo Morales Ayma (Spanish: [xwan ˈeβo moˈɾales ˈajma]; born 26 October 1959) is a Bolivian politician, trade union organizer, and former cocalero coca farmer who served as the 65th president of Bolivia from 2006 to 2019. Widely regarded as the country's first president to come from its indigenous population, his administration worked towards the implementation of left-wing policies, focusing on safeguarding the legal rights and improving the socioeconomic conditions of Bolivia's previously marginalized indigenous majority and combating the political influence of the United States and resource-extracting multinational corporations. Ideologically a socialist, he led the Movement for Socialism (MAS) party from 1998 to 2024.

Born to an Aymara family of subsistence farmers in Isallawi, Orinoca Canton, Morales undertook a basic education and mandatory military service before moving to the Chapare in 1978. Growing coca and becoming a trade unionist, he rose to prominence in the campesino ("rural laborer") union. In that capacity, he campaigned against joint U.S.–Bolivian attempts to eradicate coca as part of the war on drugs, denouncing these as an imperialist violation of indigenous Andean culture. His involvement in anti-government direct action protests resulted in multiple arrests. Morales entered electoral politics in 1995, was elected to Congress in 1997 and became leader of MAS in 1998. Coupled with populist rhetoric, he campaigned on issues affecting indigenous and poor communities, advocating land reform and more equal redistribution of money from Bolivian gas extraction. He gained increased visibility through the Cochabamba Water War and the Gas War. In 2002, he was expelled from Congress for encouraging anti-government protests, although he came second in that year's presidential election.

Erythroxylaceae (the coca family) is a family of flowering trees and shrubs consisting of 4 genera and 271 species, native to Africa and South America. The four genera are Aneulophus Benth., Erythroxylum P.Browne, Nectaropetalum Engl., and Pinacopodium Exell & Mendonça. The best-known species are the coca plants, including the species Erythroxylum coca, the source of the substance coca.

Coca-Cola, or Coke, is a cola soft drink manufactured by the Coca-Cola Company. In 2013, Coke products were sold in over 200 countries and territories worldwide, with consumers drinking more than 1.8 billion company beverage servings each day. Coca-Cola ranked No. 94 in the 2024 Fortune 500 list of the largest United States corporations by revenue. Based on Interbrand's "best global brand" study of 2023, Coca-Cola was the world's sixth most valuable brand.

Originally marketed as a temperance drink and intended as a patent medicine, Coca-Cola was invented in the late 19th century by John Stith Pemberton in Atlanta. In 1888, Pemberton sold the ownership rights to Asa Griggs Candler, a businessman, whose marketing tactics led Coca-Cola to its dominance of the global soft-drink market throughout the 20th and 21st centuries. The name refers to two of its original ingredients: coca leaves and kola nuts (a source of caffeine). The formula of Coca-Cola remains a trade secret; however, a variety of reported recipes and experimental recreations have been published. The secrecy around the formula has been used by Coca-Cola as a marketing aid because only a handful of anonymous employees know the formula. The drink has inspired imitators and created a whole classification of soft drink: colas.

An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness. They may be divided into two broad classes: general anesthetics, which result in a reversible loss of consciousness, and local anesthetics, which cause a reversible loss of sensation for a limited region of the body without necessarily affecting consciousness.

A wide variety of drugs are used in modern anesthetic practice. Many are rarely used outside anesthesiology, but others are used commonly in various fields of healthcare. Combinations of anesthetics are sometimes used for their synergistic and additive therapeutic effects. Adverse effects, however, may also be increased. Anesthetics are distinct from analgesics, which block only sensation of painful stimuli. Analgesics are typically used in conjunction with anesthetics to control pre-, intra-, and postoperative pain.

The Convention on Psychotropic Substances of 1971 is a United Nations treaty designed to control psychoactive drugs such as amphetamine-type stimulants, barbiturates, benzodiazepines, and psychedelics signed in Vienna, Austria on 21 February 1971. The Single Convention on Narcotic Drugs of 1961 did not ban the many newly discovered psychotropics, since its scope was limited to drugs with cannabis, coca and opium-like effects.

During the 1960s, such drugs became widely available, and government authorities opposed this for numerous reasons, arguing that along with negative health effects, drug use led to lowered moral standards. The Convention, which contains import and export restrictions and other rules aimed at limiting drug use to scientific and medical purposes, came into force on 16 August 1976. As of 2013, 183 member states are Parties to the treaty. The treaty is not self-implementing; individual countries must pass domestic laws to enact punishments and restrictions. Though not all scheduled substances are restricted in all signatory countries, many laws have been passed to implement or exceed the requirements of the Convention, including the Canadian Controlled Drugs and Substances Act, the UK Misuse of Drugs Act 1971 and the U.S. Psychotropic Substances Act. Adolf Lande, under the direction of the United Nations Office of Legal Affairs, prepared the Commentary on the Convention on Psychotropic Substances. The Commentary, published in 1976, is an aid to interpreting the treaty and constitutes a key part of its legislative history.

Khat (Catha edulis), also known as Bushman's tea, especially in South Africa, is a flowering plant native to eastern and southeastern Africa. It has a history of cultivation originating in the Harar area (present day eastern Ethiopia) and subsequently introduced at different times to countries nearby in East Africa and Southern Arabia, most notably Yemen. Cultivated by farmers, its leaves are sold on the market to be chewed as a recreational stimulant. The world's largest consumers are Eastern Africans, particularly Somalis, and nearby Yemen, with the largest producers/exporters being Ethiopia and Kenya.

Khat contains the alkaloid cathinone, a stimulant which causes greater sociability, excitement, mild loss of appetite and mild euphoria. Among communities from the areas where the plant is native, khat-chewing has historical relevance (as a social custom, especially among men) dating back thousands of years, analogous—but slightly different—to the use of coca leaves in South America's Andes Mountains or the betel nut preparations in South Asia.