Cerebellum in the context of "Ataxia"

The human brain is the central organ of the nervous system, and with the spinal cord, comprises the central nervous system. It consists of the cerebrum, the brainstem and the cerebellum. The brain controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sensory nervous system. The brain integrates sensory information and coordinates instructions sent to the rest of the body.

The cerebrum, the largest part of the human brain, consists of two cerebral hemispheres. Each hemisphere has an inner core composed of white matter, and an outer surface – the cerebral cortex – composed of grey matter. The cortex has an outer layer, the neocortex, and an inner allocortex. The neocortex is made up of six neuronal layers, while the allocortex has three or four. Each hemisphere is divided into four lobes – the frontal, parietal, temporal, and occipital lobes. The frontal lobe is associated with executive functions including self-control, planning, reasoning, and abstract thought, while the occipital lobe is dedicated to vision. Within each lobe, cortical areas are associated with specific functions, such as the sensory, motor, and association regions. Although the left and right hemispheres are broadly similar in shape and function, some functions are associated with one side, such as language in the left and visual-spatial ability in the right. The hemispheres are connected by commissural nerve tracts, the largest being the corpus callosum.

The cerebrum (pl.: cerebra), telencephalon or endbrain is the largest part of the brain, containing the cerebral cortex (of the two cerebral hemispheres) as well as several subcortical structures, including the hippocampus, basal ganglia, and olfactory bulb. In the human brain, the cerebrum is the uppermost region of the central nervous system. The cerebrum develops prenatally from the forebrain (prosencephalon). In mammals, the dorsal telencephalon, or pallium, develops into the cerebral cortex, and the ventral telencephalon, or subpallium, becomes the basal ganglia. The cerebrum is also divided into approximately symmetric left and right cerebral hemispheres.

With the assistance of the cerebellum, the cerebrum controls all voluntary actions in the human body.

The lobes of the brain are the four major identifiable regions of the human cerebral cortex, and they comprise the surface of each hemisphere of the cerebrum. The two hemispheres are roughly symmetrical in structure, and are connected by the corpus callosum. Some sources include the insula and limbic lobe but the limbic lobe incorporates parts of the other lobes. The lobes are large areas that are anatomically distinguishable, and are also functionally distinct. Each lobe of the brain has numerous ridges, or gyri, and furrows, sulci that constitute further subzones of the cortex. The expression "lobes of the brain" usually refers only to those of the cerebrum, not to the distinct areas of the cerebellum.

Phrenology is a pseudoscience that involves the measurement of bumps on the skull to predict mental traits. It is based on the concept that the brain is the organ of the mind, and that certain brain areas have localized, specific functions or modules. It was said that the brain was composed of different muscles, so those that were used more often were bigger, resulting in the different skull shapes. This provided reasoning for the common presence of bumps on the skull in different locations. The brain "muscles" not being used as frequently remained small and were therefore not present on the exterior of the skull. Although both of those ideas have a basis in reality, phrenology generalizes beyond empirical knowledge in a way that departs from science. The central phrenological notion that measuring the contour of the skull can predict personality traits is discredited by empirical research. Developed by German physician Franz Joseph Gall in 1796, the discipline was influential in the 19th century, especially from about 1810 until 1840. The principal British centre for phrenology was Edinburgh, where the Edinburgh Phrenological Society was established in 1820.

Phrenology is today recognized as pseudoscientific. The methodological rigor of phrenology was doubtful even for the standards of its time, since many authors already regarded phrenology as pseudoscience in the 19th century. There have been various studies conducted that discredited phrenology, most of which were done with ablation techniques. Marie-Jean-Pierre Flourens demonstrated through ablation that the cerebrum and cerebellum accomplish different functions. He found that the impacted areas never carried out the functions that were proposed through phrenology. Paul Broca also discredited the idea when he discovered and named the "Broca's area": the patient's ability to produce language was lost while their ability to understand language remained intact, due to a lesion on the left frontal lobe. He concluded that this area of the brain was responsible for language production. Between Flourens and Broca, the claims to support phrenology were dismantled. Phrenological thinking was influential in the psychiatry and psychology of the 19th century. Gall's assumption that character, thoughts, and emotions are located in specific areas of the brain is considered an important historical advance toward neuropsychology. He contributed to the idea that the brain is spatially organized, but not in the way he proposed. There is a clear division of labor in the brain but none of which even remotely correlates to the size of the head or the structure of the skull. It contributed to some advancements in understanding the brain and its functions.

The hindbrain, rhombencephalon (shaped like a rhombus) is a developmental categorization of portions of the central nervous system in vertebrates. It includes the medulla, pons, and cerebellum. Together they support vital bodily processes.

The metencephalon is the embryonic part of the hindbrain that differentiates into the pons and the cerebellum. It contains a portion of the fourth ventricle and the trigeminal nerve (CN V), abducens nerve (CN VI), facial nerve (CN VII), and a portion of the vestibulocochlear nerve (CN VIII).

The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem. It is anterior and partially inferior to the cerebellum. It is a cone-shaped neuronal mass responsible for autonomic (involuntary) functions, ranging from vomiting to sneezing. The medulla contains the cardiovascular center, the respiratory center, vomiting and vasomotor centers, responsible for the autonomic functions of breathing, heart rate and blood pressure as well as the sleep–wake cycle. "Medulla" is from Latin, ‘pith or marrow’. And "oblongata" is from Latin, ‘lengthened or longish or elongated'.

During embryonic development, the medulla oblongata develops from the myelencephalon. The myelencephalon is a secondary brain vesicle which forms during the maturation of the rhombencephalon, also referred to as the hindbrain.