Cell biophysics (or cellular biophysics) is a sub-field of biophysics that focuses on physical principles underlying cell function. Sub-areas of current interest include statistical models of intracellular signaling dynamics, intracellular transport, cell mechanics (including membrane and cytoskeletal mechanics), molecular motors, biological electricity and genetic network theory. The field has benefited greatly from recent advances in live-cell molecular imaging techniques that allow spatial and temporal measurement of macromolecules and macromolecular function. Specialized imaging methods like FRET, FRAP, photoactivation and single molecule imaging have proven useful for mapping macromolecular transport, dynamic conformational changes in proteins and macromolecular interactions. Super-resolution microscopy allows imaging of cell structures below the optical resolution of light. Combining novel experimental tools with mathematical models grounded in the physical sciences has enabled significant recent breakthroughs in the field. Multiple centers across the world are advancing the research area
Cell biophysics in the context of Dielectric
In electromagnetism, a dielectric (or dielectric medium) is an electrical insulator that can be polarised by an applied electric field. When a dielectric material is placed in an electric field, electric charges do not flow through the material as they do in an electrical conductor, because they have no loosely bound, or free, electrons that may drift through the material, but instead they shift, only slightly, from their average equilibrium positions, causing dielectric polarisation. Because of dielectric polarisation, positive charges are displaced in the direction of the field and negative charges shift in the direction opposite to the field. This creates an internal electric field that reduces the overall field within the dielectric itself. If a dielectric is composed of weakly bonded molecules, those molecules not only become polarised, but also reorient so that their symmetry axes align to the field.
The study of dielectric properties concerns storage and dissipation of electric and magnetic energy in materials. Dielectrics are important for explaining various phenomena in electronics, optics, solid-state physics and cell biophysics.
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