Castle Bravo in the context of "Teller–Ulam design"

Nuclear weapons tests are experiments carried out to determine the performance of nuclear weapons and the effects of their explosion. Over 2,000 nuclear weapons tests have been carried out since 1945. Nuclear testing is a sensitive political issue. Governments have often performed tests to signal strength. Because of their destruction and fallout, testing has seen opposition by civilians as well as governments, with international bans having been agreed on. Thousands of tests have been performed, with most in the second half of the 20th century.

The first nuclear device was detonated as a test by the United States at the Trinity site in New Mexico on July 16, 1945, with a yield approximately equivalent to 20 kilotons of TNT. The first thermonuclear weapon technology test of an engineered device, codenamed Ivy Mike, was tested at the Enewetak Atoll in the Marshall Islands on November 1, 1952 (local date), also by the United States. The largest nuclear weapon ever tested was the Tsar Bomba of the Soviet Union at Novaya Zemlya on October 30, 1961, with the largest yield ever seen, an estimated 50–58 megatons.

A thermonuclear weapon, fusion weapon or hydrogen bomb (H-bomb) is a second-generation nuclear weapon, utilizing nuclear fusion. The most destructive weapons ever created, their yields typically exceed first-generation nuclear weapons by twenty times, with far lower mass and volume requirements. Characteristics of fusion reactions can make possible the use of non-fissile depleted uranium as the weapon's main fuel, thus allowing more efficient use of scarce fissile material. Its multi-stage design is distinct from the usage of fusion in simpler boosted fission weapons. The first full-scale thermonuclear test (Ivy Mike) was carried out by the United States in 1952, and the concept has since been employed by at least the five NPT-recognized nuclear-weapon states: the United States, Russia, the United Kingdom, China, and France.

The design of all thermonuclear weapons is believed to be the Teller–Ulam configuration. This relies on radiation implosion, in which X-rays from detonation of the primary stage, a fission bomb, are channelled to compress a separate fusion secondary stage containing thermonuclear fuel, primarily lithium-6 deuteride. During detonation, neutrons convert lithium-6 to helium-4 plus tritium. The heavy isotopes of hydrogen, deuterium and tritium, then undergo a reaction that releases energy and neutrons. For this reason, thermonuclear weapons are often colloquially called hydrogen bombs or H-bombs.

The anti-nuclear movement is a social movement that opposes various nuclear technologies. Some direct action groups, environmental movements, and professional organisations have identified themselves with the movement at the local, national, or international level. Major anti-nuclear groups include Campaign for Nuclear Disarmament, Friends of the Earth, Greenpeace, International Physicians for the Prevention of Nuclear War, Peace Action, Seneca Women's Encampment for a Future of Peace and Justice and the Nuclear Information and Resource Service. The initial objective of the movement was nuclear disarmament, though since the late 1960s opposition has included the use of nuclear power. Many anti-nuclear groups oppose both nuclear power and nuclear weapons. The formation of green parties in the 1970s and 1980s was often a direct result of anti-nuclear politics.

Scientists and diplomats have debated nuclear weapons policy since before the atomic bombings of Hiroshima and Nagasaki in 1945. The public became concerned about nuclear weapons testing from about 1954, following extensive nuclear testing including the Castle Bravo disaster. In 1963, many countries ratified the Partial Test Ban Treaty which prohibited atmospheric nuclear testing.

A nuclear holocaust, also known as a nuclear apocalypse, nuclear annihilation, nuclear armageddon, or atomic holocaust, is a theoretical scenario where the mass detonation of nuclear weapons causes widespread destruction and radioactive fallout, with global consequences. Such a scenario envisages large parts of the Earth becoming uninhabitable due to the effects of nuclear warfare, potentially causing the collapse of civilization, the extinction of humanity, or the termination of most biological life on Earth.

Besides the immediate destruction of cities by nuclear blasts, the potential aftermath of a nuclear war could involve firestorms, a nuclear winter, widespread radiation sickness from fallout, and/or the temporary (if not permanent) loss of much modern technology due to electromagnetic pulses. Some scientists, such as Alan Robock, have speculated that a thermonuclear war could result in the end of modern civilization on Earth, in part due to a long-lasting nuclear winter. In one model, the average temperature of Earth following a full thermonuclear war falls for several years by 7 to 8 °C (13 to 15 degrees Fahrenheit) on average.