Caldas Department in the context of Cordillera Occidental, Colombia

Antioquia (Spanish pronunciation: [anˈtjokja] ) is one of the 32 departments of Colombia, located in the central northwestern part of Colombia with a narrow section that borders the Caribbean Sea. Most of its territory is mountainous with some valleys, much of which is part of the Andes mountain range. Antioquia has been part of many territorial divisions of former countries created within the present-day territory of Colombia. Before the adoption of the Colombian Constitution of 1886, Antioquia State had a sovereign government.

The department covers an area of 63,612 km (24,561 sq mi), and has a population of 6,994,792 (2023). Antioquia borders the Córdoba Department and the Caribbean Sea to the north; Chocó to the west; the departments of Bolívar, Santander, and Boyaca to the east; and the departments of Caldas and Risaralda to the south.

Manizales (Spanish pronunciation: [maniˈsales]) is a city in central Colombia. It is the capital of the Department of Caldas, and lies near the Nevado del Ruiz volcano.

Currently, the city is the main center for the production of Colombian coffee and an important hub for higher educational institutions.

The Cordillera Occidental (English: Western Ranges) is the lowest in elevation of the three branches of the Colombian Andes. The average altitude is 2,000 m (6,600 ft) and the highest peak is Cerro Tatamá at 4,100 m (13,500 ft). The range extends from south to north dividing from the Colombian Massif in Nariño Department, passes north through Cauca, Valle del Cauca, Risaralda, Chocó, and Caldas Departments to the Paramillo Massif in Antioquia and Córdoba Departments. The cordillera is paralleled on the east by the Cauca river. From this massif the range divides further to form the Serranías de Ayapel, San Jerónimo and Abibe. Only to recede into the Caribbean plain and the Sinú River valley.

It is a direct continuation of Cordillera Occidental of Ecuador.

Nevado del Ruiz (Spanish pronunciation: [neˈβaðo ðel ˈrwis]), also known as La Mesa de Herveo (English: Mesa of Herveo, the name of the nearby town) is a volcano on the border of the departments of Caldas and Tolima in Colombia, being the highest point of both. It is located about 130 km (81 mi) west of the capital city Bogotá. It is a stratovolcano composed of many layers of lava alternating with hardened volcanic ash and other pyroclastic rocks. Volcanic activity at Nevado del Ruiz began about two million years ago, during the Early Pleistocene or Late Pliocene, with three major eruptive periods. The current volcanic cone formed during the present eruptive period, which began 150,000 years ago.

The volcano usually generates Vulcanian to Plinian eruptions, which produce swift-moving currents of hot gas and rock called pyroclastic flows. These eruptions often cause massive lahars (mud and debris flows), which pose a threat to human life and the environment. The impact of such an eruption is increased as the hot gas and lava melt the mountain's snowcap, adding large quantities of water to the flow. On November 13, 1985, a small eruption produced an enormous lahar that buried and destroyed the town of Armero in Tolima, causing an estimated 25,000 deaths. This event later became known as the Armero tragedy—the deadliest lahar in recorded history. Similar but less deadly incidents occurred in 1595 and 1845, consisting of a small explosive eruption followed by a large lahar.

Risaralda (Spanish pronunciation: [risaˈɾalda]) is a department of Colombia. It is located in the western central of the country, in the Andean region, It is part of the Coffee axis with Caldas and Quindío. Its capital is Pereira. Risaralda is very well known for the high quality of its coffee, and a booming industry: automotive, clothes, food, trading of goods and services.

It was divided from the department of Caldas in 1966. The territory is very mountainous and has many kinds of climates in a very small area. Its proximity to harbours such as Buenaventura on the Pacific Region and to the biggest cities in Colombia – Bogotá, Cali, Medellín – makes it a fast-growing economic centre.

Los Nevados National Natural Park (Spanish: Parque Nacional Natural Los Nevados) is a national park located in the Cordillera Central of the Colombian Andes. The park features Colombia's highest and northernmost active volcanoes including the glacier-capped Nevado del Ruiz, Nevado del Tolima, and Nevado de Santa Isabel, and the formerly glaciated superpáramo peaks (paramillos) of Cisne, Santa Rosa and Quindío. Other elevated structures of volcanic origin within the park are Alto La Piraña, La Olleta, Cerro España, and the Peñas de Caracoli. Cerro Bravo and Cerro Machín are located outside the park but form part of the same volcanic region.

The park is located in the departments of Caldas, Quindío, Risaralda, Tolima and spans between the municipalities Manizales, Villamaría, Santa Rosa de Cabal, Pereira, Salento, Villahermosa, Anzoátegui, Santa Isabel, Murillo, Ibagué and Casabianca.

Nevado del Huila (/nɛˈvɑːdoʊ dɛl ˈwiːlə/, Spanish pronunciation: [neˈβaðo ðel ˈwila]) at 5,364 metres (17,598 ft), is the highest volcano in Colombia, located at the tripoint of the departments of Huila, Tolima and Cauca. It is visible from the city of Cali. The andesitic volcano is located on top of the Ibagué Batholith.

After being dormant for more than 500 years, the volcano showed heavy signs of activity in 2007 and 2008. As of February 20, 2007, there were more than 7000 "minor" seismic events, and a high state of alert was in place for the departments of Cauca, Huila, Caldas and Valle del Cauca. The volcano erupted twice in April 2007, once in April 2008 and again in November 2008. Any eruption would affect the small villages around the volcano, mostly Páez, where their inhabitants still have in memory the eruption of the Nevado del Ruiz volcano and the destruction of Armero.