Byzantine–Sasanian War of 602–628 in the context of "Kavad II"

As part of the early Muslim conquests, which began under Muhammad in 622, the Rashidun Caliphate conquered the Sasanian Empire between 632 and 654. This event led to the decline of Zoroastrianism, which had been the official religion of Persia (or Iran) since the time of the Achaemenid Empire, circa 550 BC. The persecution of Zoroastrians by the early Muslims during and after this conflict prompted many of them to flee eastward to India, where they were taken as refugees by various kings.

While Arabia was witnessing the rise of Islam in the 7th century, Persia was struggling with unprecedented political, economic and social issues as well as military weakness; the Sasanian army had greatly exhausted itself in the Byzantine–Sasanian War of 602–628. Following the execution of Sasanian shah Khosrow II in 628, Persia's internal political stability began to deteriorate rapidly, leading to ten new royal claimants being enthroned within the next four years. Shortly afterwards, Persia was further devastated by the Sasanian Interregnum, a large-scale civil war that began in 628 and resulted in the government's decentralization by 632.

The Byzantine Empire's history is generally periodised from late antiquity until the Fall of Constantinople in 1453 AD. From the 3rd to 6th centuries, the Greek East and Latin West of the Roman Empire gradually diverged, marked by Diocletian's (r. 284–305) formal partition of its administration in 285, the establishment of an eastern capital in Constantinople by Constantine I in 330, and the adoption of Christianity as the state religion under Theodosius I (r. 379–395), with others such as Roman polytheism being proscribed. Although the Western half of the Roman Empire had collapsed in 476, the Eastern half remained stable and emerged as one of the most powerful states in Europe, a title it held for most of its existence. Under the reign of Heraclius (r. 610–641), the Empire's military and administration were restructured and adopted Greek for official use instead of Latin. While there was an unbroken continuity in administration and other features of Roman society, historians have often distinguished the Byzantine epoch from earlier eras in Roman history for reasons including the imperial seat moving from Rome to Constantinople and the predominance of Greek instead of Latin.

The borders of the Empire evolved significantly over its existence, as it went through several cycles of decline and recovery. During the reign of Justinian I (r. 527–565), the Empire reached its greatest extent after reconquering much of the historically Roman western Mediterranean coast, including north Africa, Italy, and Rome itself, which it held for two more centuries. During the reign of Maurice (r. 582–602), the Empire's eastern frontier was expanded and the north stabilised. However, his assassination caused a two-decade-long war with Sassanid Persia which exhausted the Empire's resources and contributed to major territorial losses during the Muslim conquests of the 7th century. In a matter of years the Empire lost its richest provinces, Egypt and Syria, to the Arabs.

Heraclius (Greek: Ἡράκλειος, romanized: Hērákleios; c. 575 – 11 February 641) was Byzantine emperor from 610 to 641. His rise to power began in 608, when he and his father, Heraclius the Elder, the Exarch of Africa, led a revolt against the unpopular emperor Phocas.

Heraclius's reign was marked by several military campaigns. The year Heraclius came to power, the empire was threatened on multiple frontiers. Heraclius immediately took charge of the Byzantine–Sasanian War of 602–628. The first battles of the campaign ended in defeat for the Byzantines; the Persian army fought their way to the Bosphorus but Constantinople was protected by impenetrable walls and a strong navy, and Heraclius was able to avoid total defeat. Soon after, he initiated reforms to rebuild and strengthen the military. Heraclius drove the Persians out of Asia Minor and pushed deep into their territory, defeating them decisively in 627 at the Battle of Nineveh. The Persian Shah Khosrow II was overthrown and executed by his son Kavad II, who soon sued for a peace treaty, agreeing to withdraw from all occupied territory. This way peaceful relations were restored to the two deeply strained empires.

Phocas (Latin: Focas; Ancient Greek: Φωκάς, romanized: Phōkás; 547 – 5 October 610) was Eastern Roman emperor from 602 to 610. Initially a middle-ranking officer in the Roman army, Phocas rose to prominence as a spokesman for dissatisfied soldiers in their disputes with the court of the Emperor Maurice. When the army rebelled in 602, Phocas emerged as the leader of the mutiny. The revolt led to the overthrow and execution of Maurice in November 602.

Phocas deeply mistrusted the uncooperative elite of Constantinople, to whom he was a usurper and a provincial boor. He therefore attempted to base his regime on relatives installed in high military and administrative positions. He immediately faced challenges in domestic and foreign affairs, and responded with little success. He dealt with domestic opposition with increasing ruthlessness that alienated ever wider circles, including some of his own household. The Sasanian Empire launched a massive invasion of the eastern provinces. Finally, the exarch of Africa, Heraclius the Elder, rebelled against Phocas and gained wide support throughout the empire. Phocas attempted to use border troops to crush the rebellion, but this only resulted in allowing invaders to break into the heartlands of the Empire. Heraclius the Elder's son, Heraclius, took Constantinople on 5 October 610, executed Phocas the same day, and declared himself emperor.