Bocas Town, Bocas del Toro in the context of Colón Island

Bocas del Toro (Spanish pronunciation: [ˈbokas ðel ˈtoɾo]; meaning "Mouths of the Bull") is a province of Panama. Its area is 4,643.9 square kilometers, comprising the mainland and nine main islands. The province consists of the Bocas del Toro Archipelago, Bahía Almirante (Almirante Bay), Chiriquí Lagoon, and adjacent mainland. The capital is the city of Bocas del Toro (or Bocas Town) on Isla Colón (Colón Island). Other major cities or towns include Almirante and Changuinola. The province has a population of 159,228 as of 2023.

Christopher Columbus and his crew first visited the area in 1502. Bocas del Toro borders the Caribbean Sea to the north, Limón Province of Costa Rica and the Naso Tjër Di Comarca to the west, Chiriquí Province to the south, and Ngöbe-Buglé Comarca to the east. The Río Sixaola forms part of the border with Costa Rica. A newly constructed bridge spans the river between Guabito and Sixaola, Costa Rica. The bridge is a border crossing used by tourists going between destinations in Bocas del Toro and Costa Rica.

Colón Island (Spanish: Isla Colón) is the northernmost and main island in the Bocas del Toro Archipelago located in Bocas del Toro Province, Panama. The capital city of the province, Bocas del Toro, is located on the island and is one of Panama's main tourist attractions with over 150,000 visitors per year and an 8% annual rate of growth in tourism.

Changuinola is a city in the Bocas del Toro Province of Panama and seat city of the Changuinola District. The city attracts tourists as a popular gateway to Bocas Town and nearby cities Almirante and Chiriqui Grande.
Changuinola is surrounded by Changuinola River and extensive banana plantations.