Battle of the Bagradas River (255 BC) in the context of Medjerda River

The First Punic War (264–241 BC) was the first of three wars fought between Rome and Carthage, the two main powers of the western Mediterranean in the early 3rd century BC. For 23 years, in the longest continuous conflict and greatest naval war of antiquity, the two powers struggled for supremacy. The war was fought primarily on the Mediterranean island of Sicily and its surrounding waters, and also in North Africa. After immense losses on both sides, the Carthaginians were defeated and Rome gained territory from Carthage.

The war began in 264 BC with the Romans gaining a foothold on Sicily at Messana (modern Messina). The Romans then pressed Syracuse, the only significant independent power on the island, into allying with them and laid siege to Carthage's main base at Akragas. A large Carthaginian army attempted to lift the siege in 262 BC but was heavily defeated at the Battle of Akragas. The Romans then built a navy to challenge the Carthaginians, and using novel tactics inflicted several defeats. A Carthaginian base on Corsica was seized, but an attack on Sardinia was repulsed; the base on Corsica was then lost. Taking advantage of their naval victories the Romans launched an invasion of North Africa, which the Carthaginians intercepted. At the Battle of Cape Ecnomus the Carthaginians were again beaten; this was possibly the largest naval battle in history by the number of combatants involved. The invasion initially went well and in 255 BC the Carthaginians sued for peace; the proposed terms were so harsh that they fought on, defeating the invaders. The Romans sent a fleet to evacuate their survivors and the Carthaginians opposed it at the Battle of Cape Hermaeum off Africa; the Carthaginians were heavily defeated. The Roman fleet, in turn, was devastated by a storm while returning to Italy, losing most of its ships and over 100,000 men.

The Roman withdrawal from Africa was the attempt by the Roman Republic in 255 BC to rescue the survivors of their defeated expeditionary force to Carthaginian Africa during the First Punic War. A large fleet commanded by Servius Fulvius Paetinus Nobilior and Marcus Aemilius Paullus successfully evacuated the survivors after defeating an intercepting Carthaginian fleet, but was struck by a storm while returning, losing most of its ships.

The Romans had invaded the Carthaginian homeland (in what is now north eastern Tunisia) in 256 BC. After initial successes, they had left a force of 15,500 men to hold their lodgement over the winter. This force, commanded by Marcus Atilius Regulus, was decisively beaten at the Battle of Tunis in the spring of 255 BC, leading to Regulus' capture. Two thousand survivors were besieged in the port of Aspis. The Roman fleet of 390 warships was sent to rescue and evacuate them. A Carthaginian fleet of 200 ships intercepted them off Cape Hermaeum (the modern Cape Bon or Ras ed-Dar), north of Aspis. The Carthaginians were defeated with 114 of their ships captured, together with their crews, and 16 sunk. Roman losses are unknown; most modern historians assume there were none.

Marcus Atilius Regulus (fl. 267 – 255 BC) was a Roman statesman and general who was a consul of the Roman Republic in 267 BC and 256 BC. Much of his career was spent fighting the Carthaginians during the first Punic War. In 256 BC, he and Lucius Manlius Vulso Longus defeated the Carthaginians at the naval battle off Cape Ecnomus; afterwards he led the Roman expedition to Africa but was defeated at the Bagradas River in spring of 255 BC. He was captured and then probably died of natural causes, with the story of his death later being much embellished.

The Battle of Panormus was fought in Sicily in 250 BC during the First Punic War between a Roman army led by Lucius Caecilius Metellus and a Carthaginian force led by Hasdrubal, son of Hanno. The Roman force of two Roman and two allied legions defending the city of Panormus defeated the much larger Carthaginian army of 30,000 men and between 60 and 142 war elephants.

The war had commenced in 264 BC with Carthage in control of much of Sicily, where most of the fighting took place. In 256–255 BC the Romans attempted to strike at the city of Carthage in North Africa, but suffered a heavy defeat by a Carthaginian army strong in cavalry and elephants. When the focus of the war returned to Sicily, the Romans captured the large and important city of Panormus in 254 BC. Thereafter they avoided battle for fear of the war elephants which the Carthaginians had shipped to Sicily. In late summer 250 BC Hasdrubal led out his army to devastate the crops of the cities of Rome's allies. The Romans withdrew to Panormus and Hasdrubal pressed on to the city walls.