The Battle of Nineveh was the climactic battle of the Byzantine–Sasanian War of 602–628.
In mid-September 627, Heraclius invaded Sasanian Mesopotamia in a surprising, risky winter campaign. Khosrow II appointed Rhahzadh as the commander of an army to confront him. Heraclius' Göktürk allies quickly deserted, while Rhahzadh's reinforcements did not arrive in time. In the ensuing battle, Rhahzadh was slain and the remaining Sasanian forces retreated.
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Heraclius (Greek: Ἡράκλειος, romanized: Hērákleios; c. 575 – 11 February 641) was Byzantine emperor from 610 to 641. His rise to power began in 608, when he and his father, Heraclius the Elder, the Exarch of Africa, led a revolt against the unpopular emperor Phocas.
Heraclius's reign was marked by several military campaigns. The year Heraclius came to power, the empire was threatened on multiple frontiers. Heraclius immediately took charge of the Byzantine–Sasanian War of 602–628. The first battles of the campaign ended in defeat for the Byzantines; the Persian army fought their way to the Bosphorus but Constantinople was protected by impenetrable walls and a strong navy, and Heraclius was able to avoid total defeat. Soon after, he initiated reforms to rebuild and strengthen the military. Heraclius drove the Persians out of Asia Minor and pushed deep into their territory, defeating them decisively in 627 at the Battle of Nineveh. The Persian Shah Khosrow II was overthrown and executed by his son Kavad II, who soon sued for a peace treaty, agreeing to withdraw from all occupied territory. This way peaceful relations were restored to the two deeply strained empires.
The Byzantine–Sasanian War of 602–628, also called the Last Great War of Antiquity, was fought between the Byzantine Empire and the Sasanian Empire. It was the final and most devastating conflict of the Roman–Persian wars (54 BC – AD 628). The previous war between the two powers had ended in 591 after the emperor Maurice helped the Sasanian king Khosrow II regain his throne. In 602, Maurice was murdered by his political rival Phocas. Khosrow declared war, ostensibly to avenge the death of the deposed emperor Maurice. This became a decades-long conflict, the longest war in the series, and was fought throughout the Middle East, the Aegean Sea, and before the walls of Constantinople itself.
From 602 to 622, the Sassanians gradually conquered much of the Levant, parts of Anatolia, and—for the first time—Egypt and several islands in the Aegean Sea. The counter-attacks of the new Byzantine emperor Heraclius from 622 to 626 eventually forced the Persians onto the defensive. Allied with the Avars and Slavs, the Persians attempted to take Constantinople in 626, but were defeated. In 627, allied with Turks, Heraclius invaded the heartland of Persia. After the Battle of Nineveh (627), Iranian forces were finally broken, forcing civil war-torn Persia to seek peace.