Ayman al-Zawahiri in the context of "Egyptian Islamic Jihad"

Al-Qaeda is a pan-Islamist militant organization led by Sunni Islamist jihadists who self-identify as a vanguard spearheading a global Islamist revolution to unite the Muslim world under a supra-national Islamic caliphate. Its membership is mostly composed of Arabs but also includes people from other ethnic groups. Al-Qaeda has mounted attacks on civilian and military targets of the U.S. and its allies; such as the 1998 US embassy bombings, the USS Cole bombing, and the September 11 attacks. It has been designated a terrorist organization by the United Nations and over two dozen countries around the world.

The organization was founded in a series of meetings held in Peshawar during 1988, attended by Abdullah Azzam, Osama bin Laden, Muhammad Atef, Ayman al-Zawahiri and other veterans of the Soviet–Afghan War. Building upon the networks of Maktab al-Khidamat, the founding members decided to create an organization named "Al-Qaeda" to serve as a "vanguard" for jihad. When Saddam Hussein invaded and occupied Kuwait in 1990, bin Laden offered to support Saudi Arabia by sending his Mujahideen fighters. His offer was rebuffed by the Saudi government, which instead sought the aid of the United States. The stationing of U.S. troops in the Arabian Peninsula prompted bin Laden to declare a jihad against both the rulers of Saudi Arabia – whom he denounced as murtadd (apostates) – and against the US. From 1992, al-Qaeda established its headquarters in Sudan until it was expelled in 1996. It then shifted its base to the Taliban-ruled Afghanistan and later expanded to other parts of the world, primarily in the Middle East and South Asia. In 1996 and 1998, bin Laden issued two fatāwā that demanded the withdrawal of U.S. troops from Saudi Arabia.

Religious fanaticism or religious extremism is a pejorative designation used to indicate uncritical zeal or obsessive enthusiasm that is related to one's own, or one's group's, devotion to a religion – a form of human fanaticism that could otherwise be expressed in one's other involvements and participation, including employment, role, and partisan affinities. In psychiatry, the term hyperreligiosity is used. Historically, the term was applied in Christian antiquity to denigrate non-Christian religions, and subsequently acquired its current usage with the Age of Enlightenment.

Qutbism is an exonym that refers to the Sunni Islamist beliefs and ideology of Sayyid Qutb, a leading Islamist revolutionary of the Muslim Brotherhood who was executed by the Egyptian government of Gamal Abdel Nasser in 1966. Influenced by the doctrines of earlier Islamists like Hasan al-Banna and Maududi, Qutbism advocates Islamic extremist violence in order to establish an Islamic government, in addition to promoting offensive Jihad. Qutbism has been characterized as an Islamofascist and Islamic terrorist ideology.

Sayyid Qutb's treatises deeply influenced numerous jihadist ideologues and organizations across the Muslim world. Qutbism has gained prominence due to its influence on notable Jihadist figures of contemporary era such as Abdullah Azzam, Osama bin Laden, Ayman al-Zawahiri, and Saif al-Adel. Its ideas have also been adopted by the Salafi-jihadist terrorist organization Islamic State (ISIL). It was one inspiration that influenced Ruhollah Khomeini in the development of his own ideology, Khomeinism.

Mullah Hibatullah Akhundzada (Pashto; Dari: هبت الله آخندزاده, born 19 October 1967), also alternatively spelled as Haibatullah Akhunzada, is an Afghan cleric who is the supreme leader of Afghanistan under the Taliban government. He has led the Taliban since 2016, and came to power with its victory over U.S.-backed forces in the 2001–2021 war. A highly reclusive figure, he has almost no digital footprint except for an unverified photograph and several audio recordings of speeches.

Akhundzada is well known for his fatwas on Taliban matters. Unlike many Taliban leaders, Akhundzada did not have any experience in actual combat, although one of his sons was a suicide bomber. He was an Islamic judge of the Sharia courts of the 1996–2001 Taliban government. He was chosen to lead the Taliban’s shadow court system at the start of the Taliban insurgency, and remained in that post until being elected supreme leader of the Taliban in May 2016. Ayman al-Zawahiri, the leader of al-Qaeda, backed Akhundzada as the Amir al-Mu'minin, which strengthened Akhundzada's jihadist reputation among the Taliban's allies. In 2019, Akhundzada appointed Abdul Ghani Baradar to lead peace talks with the U.S., which led to the 2020 signing of the Doha Agreement that cleared the way for the full withdrawal of United States troops from Afghanistan.

The Maktab al-Khidamat, also Maktab Khadamāt al-Mujāhidīn al-'Arab (Arabic: مكتب الخدمات or مكتب خدمات المجاهدين العرب, MAK), also known as the Afghan Services Bureau, was founded in 1984 by Abdullah Azzam, Wa'el Hamza Julaidan, Osama bin Laden and Ayman al-Zawahiri to raise funds and recruit foreign mujahideen for the war against the Soviets in Afghanistan. MAK became the forerunner to al-Qaeda and was instrumental in creating the fundraising and recruitment network that benefited Al-Qaeda during the 1990s.