An avunculate marriage (or uncle/aunt-niece/nephew marriage) is a marriage with a parent's sibling or with one's sibling's child—i.e., an uncle or aunt marrying their niece or nephew. Such a marriage may occur between biological (consanguine) relatives or between persons related by marriage (affinity). In some countries, avunculate marriages are prohibited by law, while in others marriages between such biological relatives are both legal and common, though now far less common.
If the partners in an avunculate marriage are biologically related, they normally have the same genetic relationship as half-siblings, or a grandparent and grandchild—that is they share approximately 25% of their genetic material. (They are therefore more closely related than partners in a marriage between first cousins or between granduncle/grandaunt and grandniece/grandnephew, in which on average the members share 12.5% of inherited genetic material, but less than that of a marriage between, for instance, cousin-siblings, in which the partners share 37.5% of their inherited genetic material.)