Automated Transfer Vehicle in the context of "Progress (spacecraft)"

Orion (Orion Multi-Purpose Crew Vehicle or Orion MPCV) is a partially reusable crewed spacecraft used in NASA's Artemis program. The spacecraft consists of a Crew Module (CM) space capsule designed by Lockheed Martin that is paired with a European Service Module (ESM) manufactured by Airbus Defence and Space. Capable of supporting a crew of four beyond low Earth orbit, Orion can last up to 21 days undocked and up to six months docked. It is equipped with solar panels, an automated docking system, and glass cockpit interfaces. Orion is launched atop a Space Launch System (SLS) rocket, with a tower launch escape system.

Orion was conceived in the early 2000s by Lockheed Martin as a proposal for the Crew Exploration Vehicle (CEV) to be used in NASA's Constellation program and was selected by NASA in 2006. Following the cancellation of the Constellation program in 2010, Orion was extensively redesigned for use in NASA's Journey to Mars initiative; later named Moon to Mars. The SLS became Orion's primary launch vehicle, and the service module was replaced with a design based on the European Space Agency's Automated Transfer Vehicle. A development version of Orion's crew module was launched in 2014 during Exploration Flight Test-1, while at least four test articles were produced. Orion was primarily designed by Lockheed Martin Space Systems in Littleton, Colorado, with former Space Shuttle engineer Julie Kramer White at NASA as Orion's chief engineer.

The European Service Module (ESM) is the service module component of the Orion spacecraft, serving as its primary power and propulsion component until it is discarded at the end of each mission. In January 2013, NASA announced that the European Space Agency (ESA) will contribute the service module for Artemis I, based on the ESA's Automated Transfer Vehicle (ATV). It was delivered by Airbus Defence and Space in Bremen, in northern Germany to NASA at the end of 2018. After approval of the first module, the ESA will provide the ESMs from Artemis II to Artemis VI. However, the Trump administration has called for the termination of Orion spacecraft program after Artemis III.

The module's first flight was Artemis I, the first major milestone in NASA's Artemis program to return humans to the Moon, on November 16, 2022. The Space Launch System launched Orion toward the Moon, where the ESM placed the spacecraft into distant retrograde orbit around the Moon, and subsequently extracted it from that orbit and sent it back to Earth.

Cygnus is an expendable American uncrewed cargo spacecraft developed for International Space Station (ISS) resupply missions. It was originally built by Orbital Sciences Corporation with financial support from NASA under the Commercial Orbital Transportation Services (COTS) program. The spacecraft consists of a pressurized cargo module—based largely on the Multi-Purpose Logistics Module and built by Thales Alenia Space—paired with a service module derived from Orbital's GEOStar, a satellite bus. Following a successful demonstration flight in 2013, Orbital was awarded a Commercial Resupply Services (CRS) contract.

Over time, Cygnus has been upgraded to increase its size and capabilities. The Enhanced Cygnus variant debuted in 2015, and the further enlarged Cygnus XL entered service in 2025. Features added over time include reboost capability to raise the ISS orbit, the ability to support late cargo loading shortly before launch, and the option to conduct secondary missions after undocking. Each mission ends with a controlled destructive reentry, which also provides a means of disposing of waste generated aboard the station. Alongside Cygnus, other ISS resupply spacecraft have included the Russian Progress, the European Automated Transfer Vehicle, the Japanese H-II Transfer Vehicle, and the American SpaceX Dragon.