Assyrian Americans (Syriac: ܣܘܼܖ̈ܵܝܹܐ ܐܲܡܪ̈ܝܼܟܵܝܹܐ) are individuals of ethnic Assyrian ancestry born or residing within the United States. Assyrians are an ethnic group native to Mesopotamia in West Asia who descend from their ancient counterparts, directly originating from the ancient indigenous Mesopotamians of Akkad and Sumer who first developed the independent civilization in northern Mesopotamia that would become Assyria in 2600 BC. Modern Assyrians often culturally self-identify as Syriacs, Chaldeans, or Arameans for religious and tribal identification. The first significant wave of Assyrian immigration to the United States was due to the Sayfo genocide in the Assyrian homeland in 1914–1924.
The largest Assyrian diaspora in the United States is located in Metro Detroit, with a figure of 150,000. High concentrations are also located in Phoenix, San Jose, Modesto, San Diego, Los Angeles, Turlock, and Chicago among others.