Apaseo el Grande is a city and municipality located in Guanajuato, Mexico. The municipality covers 415.26 square kilometres (160 sq mi). It is bordered on the north by Comonfort and San Miguel de Allende, on the east by Querétaro in the State of Querétaro, on the south by Apaseo el Alto, and on the west by Celaya. The municipality had a population of 85,319 inhabitants according to the 2010 census.
In pre-Columbian times, the region was known as Andahe ("Close to the water") and Atlayahualco ("Place where water flows") by the Otomí and Nahua inhabitants. It was eventually known as Apatzeo ("Yellow flower") by the Purépecha. Following the Spanish conquest c.1525, Apaseo was the first town founded in what is now the state of Guanajuato. It received its present name of Apaseo el Grande in 1957, to avoid confusion with the neighboring town of Apaseo el Alto.
