The Allegheny River (/ˌælɪˈɡeɪni/ AL-ig-AY-nee; Seneca: Ohi:yo'; Unami: Alikehane) is a 325-mile-long (523 km) tributary of the Ohio River that is located in western Pennsylvania and New York in the United States. It runs from its headwaters just below the middle of Pennsylvania's northern border, northwesterly into New York, then in a zigzag southwesterly across the border and through Western Pennsylvania to join the Monongahela River at the Forks of the Ohio at Point State Park in Downtown Pittsburgh, Pennsylvania.
The Allegheny River is, by volume, the main headstream of both the Ohio and Mississippi Rivers. Historically, the Allegheny was considered to be the upper Ohio River by both Native Americans and European settlers.