Al-‘Uzzá in the context of "Nakhla (Saudi Arabia)"

In pre-Islamic Arabia, the dominant religious practice was that of Arab polytheism, which was based on the veneration of various deities and spirits, such as the god Hubal and the goddesses al-Lāt, al-‘Uzzā, and Manāt. Worship was centred on local shrines and temples, most notably including the Kaaba in Mecca. Deities were venerated and invoked through pilgrimages, divination, and ritual sacrifice, among other traditions. Different theories have been proposed regarding the role of "Allah" (a word in Arabic that is now chiefly associated with God in Islam) in the Meccan religion. Many of the physical descriptions of the pre-Islamic gods and goddesses are traced to idols, especially near the Kaaba, which is said to have contained up to 360 of them.

Other religions—namely Christianity, Judaism, and Zoroastrianism—were also represented in the region. The influence of the Roman Empire and the Kingdom of Aksum enabled the nurturing of Christian communities in northwestern, northeastern, and southern Arabia. In the other areas of the Arabian Peninsula, Christianity did not have as much of a presence, though it did secure some converts, and with the exception of Nestorianism in the northeast and around the Persian Gulf, the dominant form of the religion was Miaphysitism. Since the beginning of the Roman era, Jewish migration into Arabia had become increasingly frequent, resulting in the establishment of a prominent Jewish diaspora community, which was supplemented by local converts. Over time, Judaism grew throughout southern Arabia and the northwestern Hejaz.

Manāt (Arabic: مناة, pronounced [maˈnaːh] (pausa) or [maˈnaːt], Old Arabic: [manaˈwat]; also transliterated as Manāh) was a pre-Islamic Arabian goddess worshipped in the Arabian Peninsula before the rise of Islam and the Islamic prophet Muhammad in the 6/7th century. She was among Mecca's three chief goddesses, alongside her sisters, Al-Lat and Al-‘Uzzá, and among them, she was the original and the oldest.