Acute radiation syndrome in the context of "Complete blood count"

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⭐ Core Definition: Acute radiation syndrome

Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time. Symptoms can start within an hour of exposure, and can last for several months. Early symptoms are usually nausea, vomiting and loss of appetite. In the following hours or weeks, initial symptoms may appear to improve, before the development of additional symptoms, after which either recovery or death follows.

ARS involves a total dose of greater than 0.7 Gy (70 rad), that generally occurs from a source outside the body, delivered within a few minutes. Sources of such radiation can occur accidentally or intentionally. They may involve nuclear reactors, cyclotrons, certain devices used in cancer therapy, nuclear weapons, or radiological weapons. It is generally divided into three types: bone marrow, gastrointestinal, and neurovascular syndrome, with bone marrow syndrome occurring at 0.7 to 10 Gy, and neurovascular syndrome occurring at doses that exceed 50 Gy. The cells that are most affected are generally those that are rapidly dividing. At high doses, this causes DNA damage that may be irreparable. Diagnosis is based on a history of exposure and symptoms. Repeated complete blood counts (CBCs) can indicate the severity of exposure.

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Acute radiation syndrome in the context of Radiation shield

Radiation protection, also known as radiological protection, is defined by the International Atomic Energy Agency (IAEA) as "The protection of people from harmful effects of exposure to ionizing radiation, and the means for achieving this". Exposure can be from a source of radiation external to the human body or due to internal irradiation caused by the ingestion of radioactive contamination.

Ionizing radiation is widely used in industry and medicine, and can present a significant health hazard by causing microscopic damage to living tissue. There are two main categories of ionizing radiation health effects. At high exposures, it can cause "tissue" effects, also called "deterministic" effects due to the certainty of them happening, conventionally indicated by the unit gray and resulting in acute radiation syndrome. For low level exposures there can be statistically elevated risks of radiation-induced cancer, called "stochastic effects" due to the uncertainty of them happening, conventionally indicated by the unit sievert.

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Acute radiation syndrome in the context of Gray (unit)

The gray (symbol: Gy) is the unit of ionizing radiation dose in the International System of Units (SI), defined as the absorption of one joule of radiation energy per kilogram of matter.

It is used as a unit of the radiation quantity absorbed dose that measures the energy deposited by ionizing radiation in a unit mass of absorbing material, and is used for measuring the delivered dose in radiotherapy, food irradiation and radiation sterilization. It is important in predicting likely acute health effects, such as acute radiation syndrome and is used to calculate equivalent dose using the sievert, which is a measure of the stochastic health effect on the human body.

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Acute radiation syndrome in the context of Castle Bravo

Castle Bravo was the first in a series of high-yield thermonuclear weapon design tests conducted by the United States at Bikini Atoll, Marshall Islands, as part of Operation Castle. Detonated on 1 March 1954, the device remains the most powerful nuclear device ever detonated by the United States and the first lithium deuteride-fueled thermonuclear weapon tested using the Teller–Ulam design. Castle Bravo's yield was 15 megatons of TNT [Mt] (63 PJ), 2.5 times the predicted 6 Mt (25 PJ), due to unforeseen additional reactions involving lithium-7, which led to radioactive contamination in the surrounding area.

Radioactive nuclear fallout, the heaviest of which was in the form of pulverized surface coral from the detonation, fell on residents of Rongelap and Utirik atolls, while the more particulate and gaseous fallout spread around the world. The inhabitants of the islands were evacuated three days later and suffered radiation sickness. Twenty-three crew members of the Japanese fishing vessel Daigo Fukuryū Maru ("Lucky Dragon No. 5") were also contaminated by the heavy fallout, experiencing acute radiation syndrome, including the death six months later of Kuboyama Aikichi, the boat's chief radioman. The blast incited a strong international reaction over atmospheric thermonuclear testing.

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Acute radiation syndrome in the context of Nuclear holocaust

A nuclear holocaust, also known as a nuclear apocalypse, nuclear annihilation, nuclear armageddon, or atomic holocaust, is a theoretical scenario where the mass detonation of nuclear weapons causes widespread destruction and radioactive fallout, with global consequences. Such a scenario envisages large parts of the Earth becoming uninhabitable due to the effects of nuclear warfare, potentially causing the collapse of civilization, the extinction of humanity, or the termination of most biological life on Earth.

Besides the immediate destruction of cities by nuclear blasts, the potential aftermath of a nuclear war could involve firestorms, a nuclear winter, widespread radiation sickness from fallout, and/or the temporary (if not permanent) loss of much modern technology due to electromagnetic pulses. Some scientists, such as Alan Robock, have speculated that a thermonuclear war could result in the end of modern civilization on Earth, in part due to a long-lasting nuclear winter. In one model, the average temperature of Earth following a full thermonuclear war falls for several years by 7 to 8 °C (13 to 15 degrees Fahrenheit) on average.

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Acute radiation syndrome in the context of Vasily Ignatenko

Vasily Ivanovich Ignatenko (Ukrainian: Василь Іванович Ігнатенко; Belarusian: Васіль Іванавіч Ігнаценка; Russian: Василий Иванович Игнатенко; 13 March 1961 – 13 May 1986) was a Soviet firefighter who was among the first responders to the Chernobyl disaster.

He worked as an electrician before being conscripted into the Soviet Armed Forces in 1980, where he completed his two years of service as a military firefighter. Afterwards, he took up employment as a paramilitary firefighter with Fire Brigade No. 6, based in Pripyat. On 26 April 1986, Ignatenko's fire brigade was involved in mitigating the immediate aftermath of the Chernobyl disaster; fighting the fires that broke out following the initial explosion of Reactor 4 at the Chernobyl Nuclear Power Plant. While on site, Ignatenko received a high dose of radiation, leading to his death at a radiological hospital in Moscow eighteen days later.

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Acute radiation syndrome in the context of Dirty bomb

A dirty bomb or radiological dispersal device is a radiological weapon that combines radioactive material with conventional explosives. The purpose of the weapon is to contaminate the area around the dispersal agent/conventional explosion with radioactive material, serving primarily as an area denial device against civilians. It is not to be confused with a nuclear explosion, such as a fission bomb, which produces blast effects far in excess of what is achievable by the use of conventional explosives. Unlike the rain of radioactive material from a typical fission bomb, a dirty bomb's radiation can be dispersed only within a few hundred meters or a few miles of the explosion.

Dirty bombs have never been used, only tested. They are designed to disperse radioactive material over a certain area. They act through the effects of radioactive contamination on the environment and related health effects of radiation poisoning in the affected populations. The containment and decontamination of victims, as well as decontamination of the affected area require considerable time and expenses, rendering areas partly unusable and causing economic damage. Dirty bombs might be used to create mass panic as a weapon of terror.

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