Abu Talib ibn Abd al-Muttalib in the context of "Patronymic"

Muhammad (c. 570 – 8 June 632 CE) was an Arab religious, military and political leader and the founder of Islam. According to Islam, he was a prophet who was divinely inspired to preach and confirm the monotheistic teachings of Adam, Noah, Abraham, Moses, Jesus, and other prophets. He is believed by Muslims to be the Seal of the Prophets, and along with the Quran, his teachings and normative examples form the basis for Islamic religious belief.

According to the traditional account, Muhammad was born in Mecca to the aristocratic Banu Hashim clan of the Quraysh. He was the son of Abdullah ibn Abd al-Muttalib and Amina bint Wahb. His father, Abdullah, the son of tribal leader Abd al-Muttalib ibn Hashim, died around the time Muhammad was born. His mother Amina died when he was six, leaving Muhammad an orphan. He was raised under the care of his grandfather, Abd al-Muttalib, and paternal uncle, Abu Talib. In later years, he would periodically seclude himself in a mountain cave named Hira for several nights of prayer. When he was 40, in c. 610, Muhammad reported being visited by Gabriel in the cave and receiving his first revelation from God. In 613, Muhammad started preaching these revelations publicly, proclaiming that "God is One", that complete "submission" (Islām) to God (Allāh) is the right way of life (dīn), and that he was a prophet and messenger of God, similar to other prophets in Islam.

Ali ibn Abi Talib (Arabic: عَلِيُّ بْن أَبِي طَالِب, romanized: ʿAlī ibn Abī Ṭālib) (c. 600 – 661 CE) was the fourth Rashidun caliph who ruled from 656 CE until his assassination in 661, as well as the first Shia Imam. He was the cousin and son-in-law of the Islamic prophet Muhammad. Born to Abu Talib ibn Abd al-Muttalib and Fatima bint Asad, Ali was raised by his elder cousin Muhammad and was among the first to accept his teachings.

Ali played a pivotal role in the early years of Islam when Muslims were severely persecuted in Mecca. After the immigration (hijra) to Medina in 622, Muhammad gave his daughter Fatima to Ali in marriage and swore a pact of brotherhood with him. Ali served as Muhammad's secretary and deputy in this period, and was the flag bearer of his army. Numerous sayings of Muhammad praise Ali, the most controversial of which was uttered in 632 at the Ghadir Khumm, "Whoever I am his mawla, then Ali is his mawla." The interpretation of the polysemous Arabic word mawla is disputed: For Shia Muslims, Muhammad thus invested Ali with his religious and political authority, while Sunni Muslims view this as a mere statement of friendship and rapport. When Muhammad died in the same year, a group of Muslims met in the absence of Ali and appointed Abu Bakr (r. 632–634) as their leader. Ali later relinquished his claims to leadership and resigned from public life during the reigns of Abu Bakr and his successor, Umar (r. 634–644). Even though his advice was occasionally sought, the conflicts between Ali and the first two caliphs are epitomized by his refusal to follow their practices. This refusal cost Ali the caliphate to the benefit of Uthman (r. 644–656), who was thus appointed to succeed Umar by the electoral council. Ali was also highly critical of Uthman, who was widely accused of nepotism and corruption. Yet Ali also repeatedly mediated between the caliph and the provincial dissidents angered by his policies.

Husayn ibn Ali (Arabic: الحسين بن علي, romanized: al-Ḥusayn ibn ʿAlī; 11 January 626 – 10 October 680 CE) was a social, political and religious leader in early medieval Arabia. The grandson of the Islamic prophet Muhammad and an Alid (the son of Ali ibn Abi Talib and Muhammad's daughter Fatima), as well as a younger brother of Hasan ibn Ali, Husayn is regarded as the third Imam in Shia Islam after his brother, Hasan, and before his son, Ali al-Sajjad. Husayn is a prominent member of the Ahl al-Bayt and is also considered to be a member of the Ahl al-Kisa and a participant in the event of the mubahala. Muhammad described him and his brother, Hasan, as the leaders of the youth of paradise.

During the caliphate of Ali, Husayn accompanied him in wars. After the assassination of Ali, he obeyed his brother in recognizing the Hasan–Mu'awiya I treaty, despite it being suggested to do otherwise. In the nine-year period between Hasan's abdication in AH 41 (660) and his death in AH 49 or 50 (669 or 670), Hasan and Husayn retreated to Medina, trying to keep aloof from political involvement for or against Mu'awiya I. After the death of Hasan, when Iraqis turned to Husayn, concerning an uprising, Husayn instructed them to wait as long as Mu'awiya was alive due to Hasan's peace treaty with him.

Fatima bint Asad (Arabic: فَاطِمَة بِنْت أَسَد Fāṭima bint ʾAsad c. 555–626 CE) was the wife of Abu Talib and the mother of their son Ali ibn Abi Talib.

Fatima bint Asad and her husband, Abu Talib, acted as the Prophet's adopted parents for fifteen years, after Muhammad had lost his mother when he was six (his father had died before he was born). Years later, Muhammad repaid the love he had received from Fatima bint Asad by adopting Ali, Fatima's youngest child, as his son.

Sayyid is an honorific title of Hasanid and Husaynid lineage, recognized as descendants of the Islamic prophet Muhammad through his daughter Fatima and Ali's sons Hasan and Husayn. The title may also refer to the descendants of the family of the Bani Hashim through the Prophet's great-grandfather Hashim, and others including Hamza, Abbas, Abu Talib, and Asad ibn Hashim.

See also Sharif, which has a good description of three types of identification for that term and co-relates to this term. In its narrowest sense, a sayyid is a descendant of Husayn ibn Ali, but the term is also more generally used for descendants of The Prophet.